PARP-1-Associated Pathological Processes: Inhibition by Natural Polyphenols

Poly (ADP-ribose) polymerase-1 (PARP-1) is a nuclear enzyme involved in processes of cell cycle regulation, DNA repair, transcription, and replication. Hyperactivity of PARP-1 induced by changes in cell homeostasis promotes development of chronic pathological processes leading to cell death during v...

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Bibliographic Details
Main Authors: Natalya V. Maluchenko, Alexey V. Feofanov, Vasily M. Studitsky
Format: article
Language:EN
Published: MDPI AG 2021
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Online Access:https://doaj.org/article/26611aef751b49b9ac76fbd4a016704f
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