PARP-1-Associated Pathological Processes: Inhibition by Natural Polyphenols
Poly (ADP-ribose) polymerase-1 (PARP-1) is a nuclear enzyme involved in processes of cell cycle regulation, DNA repair, transcription, and replication. Hyperactivity of PARP-1 induced by changes in cell homeostasis promotes development of chronic pathological processes leading to cell death during v...
Guardado en:
Autores principales: | Natalya V. Maluchenko, Alexey V. Feofanov, Vasily M. Studitsky |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/26611aef751b49b9ac76fbd4a016704f |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
AIF, PARP-1 and MicroRNA-9 Expression in Cerebral Ischemia Associated to Alcoholism Experimental Model
por: Abrahão,Dayana Pousa Siqueira, et al.
Publicado: (2020) -
PARP Inhibitors and Haematological Malignancies—Friend or Foe?
por: Kathryn A. Skelding, et al.
Publicado: (2021) -
PARP Inhibitors: An Innovative Approach to the Treatment of Inflammation and Metabolic Disorders in Sepsis
por: Wasyluk W, et al.
Publicado: (2021) -
Optimizing the Schedule of PARP Inhibitors in Combination with <sup>177</sup>Lu-DOTATATE: A Dosimetry Rationale
por: Andreas Hallqvist, et al.
Publicado: (2021) -
Olaparib Is a Mitochondrial Complex I Inhibitor That Kills Temozolomide-Resistant Human Glioblastoma Cells
por: Luca X. Zampieri, et al.
Publicado: (2021)