Biochemical consequences of two clinically relevant ND-gene mutations in Escherichia coli respiratory complex I

Biochemical consequences of two clinically relevant ND-gene mutations in Escherichia coli respiratory complex I

Abstract NADH:ubiquinone oxidoreductase (respiratory complex I) plays a major role in energy metabolism by coupling electron transfer from NADH to quinone with proton translocation across the membrane. Complex I deficiencies were found to be the most common source of human mitochondrial dysfunction...

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Bibliographic Details
Main Authors: Franziska Nuber, Johannes Schimpf, Jean-Paul di Rago, Déborah Tribouillard-Tanvier, Vincent Procaccio, Marie-Laure Martin-Negrier, Aurélien Trimouille, Olivier Biner, Christoph von Ballmoos, Thorsten Friedrich
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/26652c8a0a244e3ead826a846ee6b58d
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https://doaj.org/article/26652c8a0a244e3ead826a846ee6b58d

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