The RGS-RhoGEFs control the amplitude of YAP1 activation by serum
Abstract Actin-dependent mechanisms drive the nuclear translocation of Yap1 to enable its co-activation of transcription factors that induce pro-growth and survival programs. While Rho GTPases are necessary for the nuclear import of YAP1, the relevant Guanine Exchange Factors (GEFs) and GTPase Activ...
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Autores principales: | Brandon S. Lane, Brigitte Heller, Morley D. Hollenberg, Clark D. Wells |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/266df4df734b483da8761711da4de944 |
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