Ideal Cardiovascular Health Metric and Its Change With Lifetime Risk of Cardiovascular Diseases: A Prospective Cohort Study

Background Cardiovascular health (CVH) status is associated with cardiovascular diseases (CVD). However, evidence for association of CVH change with risk of CVD is scarce. Methods and Results Seven metrics (smoking status, body mass index, physical activity, diet, total cholesterol, blood pressure,...

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Autores principales:	Lulin Wang, Lulu Song, Dankang Li, Ziyi Zhou, Shuohua Chen, Yingping Yang, Yonghua Hu, Youjie Wang, Shouling Wu, Yaohua Tian
Formato:	article
Lenguaje:	EN
Publicado:	Wiley 2021
Materias:	cardiovascular disease cardiovascular health status life expectancy lifetime risk Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/2686ba3ec91c4ac18a2bfd38b0480b5d
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spelling	oai:doaj.org-article:2686ba3ec91c4ac18a2bfd38b0480b5d2021-11-16T10:22:43ZIdeal Cardiovascular Health Metric and Its Change With Lifetime Risk of Cardiovascular Diseases: A Prospective Cohort Study10.1161/JAHA.121.0225022047-9980https://doaj.org/article/2686ba3ec91c4ac18a2bfd38b0480b5d2021-11-01T00:00:00Zhttps://www.ahajournals.org/doi/10.1161/JAHA.121.022502https://doaj.org/toc/2047-9980Background Cardiovascular health (CVH) status is associated with cardiovascular diseases (CVD). However, evidence for association of CVH change with risk of CVD is scarce. Methods and Results Seven metrics (smoking status, body mass index, physical activity, diet, total cholesterol, blood pressure, and fasting blood glucose) were used to evaluate the CVH status. Having 0 to 2, 3 to 4, and 5 to 7 ideal cardiovascular metrics were categorized as low, moderate, and high CVH status, respectively. Change in CVH status was assessed from 2006/2007 to 2010/2011. We calculated lifetime risk of CVD using a modified Kaplan–Meier method, and life expectancy was evaluated via the multistate lifetable method. There were 82 349 participants included in our analysis. At 35 years index age, the age‐adjusted incident rate and lifetime risk of CVD were increased with decreasing number of ideal CVH metrics. The direction of change in status of CVH was consistently associated with age‐adjusted incident rate and lifetime risk of CVD. At 35 years index age, improvement from low to moderate (37.6% [95% CI, 32.8%–42.4%]) or to high status (24.4% [95% CI, 12.7%–36.0%]) had lower lifetime risk of CVD compared with consistently low status (44.6% [95% CI, 40.8%–48.5%]). The improvement in CVH could prolong the years of life free from CVD. The pattern of incident rate and lifetime risk across change in CVH status was similar at 45 and 55 years index age. Conclusions Higher number of CVH metrics was associated with lower lifetime risk of CVD. The improvement of CVH status could reduce the lifetime risk of CVD and prolonged the year of life free from CVD.Lulin WangLulu SongDankang LiZiyi ZhouShuohua ChenYingping YangYonghua HuYoujie WangShouling WuYaohua TianWileyarticlecardiovascular diseasecardiovascular health statuslife expectancylifetime riskDiseases of the circulatory (Cardiovascular) systemRC666-701ENJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 22 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	cardiovascular disease cardiovascular health status life expectancy lifetime risk Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	cardiovascular disease cardiovascular health status life expectancy lifetime risk Diseases of the circulatory (Cardiovascular) system RC666-701 Lulin Wang Lulu Song Dankang Li Ziyi Zhou Shuohua Chen Yingping Yang Yonghua Hu Youjie Wang Shouling Wu Yaohua Tian Ideal Cardiovascular Health Metric and Its Change With Lifetime Risk of Cardiovascular Diseases: A Prospective Cohort Study
description	Background Cardiovascular health (CVH) status is associated with cardiovascular diseases (CVD). However, evidence for association of CVH change with risk of CVD is scarce. Methods and Results Seven metrics (smoking status, body mass index, physical activity, diet, total cholesterol, blood pressure, and fasting blood glucose) were used to evaluate the CVH status. Having 0 to 2, 3 to 4, and 5 to 7 ideal cardiovascular metrics were categorized as low, moderate, and high CVH status, respectively. Change in CVH status was assessed from 2006/2007 to 2010/2011. We calculated lifetime risk of CVD using a modified Kaplan–Meier method, and life expectancy was evaluated via the multistate lifetable method. There were 82 349 participants included in our analysis. At 35 years index age, the age‐adjusted incident rate and lifetime risk of CVD were increased with decreasing number of ideal CVH metrics. The direction of change in status of CVH was consistently associated with age‐adjusted incident rate and lifetime risk of CVD. At 35 years index age, improvement from low to moderate (37.6% [95% CI, 32.8%–42.4%]) or to high status (24.4% [95% CI, 12.7%–36.0%]) had lower lifetime risk of CVD compared with consistently low status (44.6% [95% CI, 40.8%–48.5%]). The improvement in CVH could prolong the years of life free from CVD. The pattern of incident rate and lifetime risk across change in CVH status was similar at 45 and 55 years index age. Conclusions Higher number of CVH metrics was associated with lower lifetime risk of CVD. The improvement of CVH status could reduce the lifetime risk of CVD and prolonged the year of life free from CVD.
format	article
author	Lulin Wang Lulu Song Dankang Li Ziyi Zhou Shuohua Chen Yingping Yang Yonghua Hu Youjie Wang Shouling Wu Yaohua Tian
author_facet	Lulin Wang Lulu Song Dankang Li Ziyi Zhou Shuohua Chen Yingping Yang Yonghua Hu Youjie Wang Shouling Wu Yaohua Tian
author_sort	Lulin Wang
title	Ideal Cardiovascular Health Metric and Its Change With Lifetime Risk of Cardiovascular Diseases: A Prospective Cohort Study
title_short	Ideal Cardiovascular Health Metric and Its Change With Lifetime Risk of Cardiovascular Diseases: A Prospective Cohort Study
title_full	Ideal Cardiovascular Health Metric and Its Change With Lifetime Risk of Cardiovascular Diseases: A Prospective Cohort Study
title_fullStr	Ideal Cardiovascular Health Metric and Its Change With Lifetime Risk of Cardiovascular Diseases: A Prospective Cohort Study
title_full_unstemmed	Ideal Cardiovascular Health Metric and Its Change With Lifetime Risk of Cardiovascular Diseases: A Prospective Cohort Study
title_sort	ideal cardiovascular health metric and its change with lifetime risk of cardiovascular diseases: a prospective cohort study
publisher	Wiley
publishDate	2021
url	https://doaj.org/article/2686ba3ec91c4ac18a2bfd38b0480b5d
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Ideal Cardiovascular Health Metric and Its Change With Lifetime Risk of Cardiovascular Diseases: A Prospective Cohort Study

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