Opposing roles for striatonigral and striatopallidal neurons in dorsolateral striatum in consolidating new instrumental actions

New instrumental learning occurs through an unexpected delivery of a rewarding stimulus or the withdrawal of a punishing stimulus. The authors show that D1 receptor-expressing medium spiny neurons (MSNs) in the anterior dorsolateral striatum encode newly learned instrumental actions whereas D2 MSNs...

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Autores principales:	Alexander C. W. Smith, Sietse Jonkman, Alexandra G. Difeliceantonio, Richard M. O’Connor, Soham Ghoshal, Michael F. Romano, Barry J. Everitt, Paul J. Kenny
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/268c60f143c3450aace33229b83ad544
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spelling	oai:doaj.org-article:268c60f143c3450aace33229b83ad5442021-12-02T18:53:15ZOpposing roles for striatonigral and striatopallidal neurons in dorsolateral striatum in consolidating new instrumental actions10.1038/s41467-021-25460-32041-1723https://doaj.org/article/268c60f143c3450aace33229b83ad5442021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25460-3https://doaj.org/toc/2041-1723New instrumental learning occurs through an unexpected delivery of a rewarding stimulus or the withdrawal of a punishing stimulus. The authors show that D1 receptor-expressing medium spiny neurons (MSNs) in the anterior dorsolateral striatum encode newly learned instrumental actions whereas D2 MSNs promote the expression of habitual actions.Alexander C. W. SmithSietse JonkmanAlexandra G. DifeliceantonioRichard M. O’ConnorSoham GhoshalMichael F. RomanoBarry J. EverittPaul J. KennyNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Alexander C. W. Smith Sietse Jonkman Alexandra G. Difeliceantonio Richard M. O’Connor Soham Ghoshal Michael F. Romano Barry J. Everitt Paul J. Kenny Opposing roles for striatonigral and striatopallidal neurons in dorsolateral striatum in consolidating new instrumental actions
description	New instrumental learning occurs through an unexpected delivery of a rewarding stimulus or the withdrawal of a punishing stimulus. The authors show that D1 receptor-expressing medium spiny neurons (MSNs) in the anterior dorsolateral striatum encode newly learned instrumental actions whereas D2 MSNs promote the expression of habitual actions.
format	article
author	Alexander C. W. Smith Sietse Jonkman Alexandra G. Difeliceantonio Richard M. O’Connor Soham Ghoshal Michael F. Romano Barry J. Everitt Paul J. Kenny
author_facet	Alexander C. W. Smith Sietse Jonkman Alexandra G. Difeliceantonio Richard M. O’Connor Soham Ghoshal Michael F. Romano Barry J. Everitt Paul J. Kenny
author_sort	Alexander C. W. Smith
title	Opposing roles for striatonigral and striatopallidal neurons in dorsolateral striatum in consolidating new instrumental actions
title_short	Opposing roles for striatonigral and striatopallidal neurons in dorsolateral striatum in consolidating new instrumental actions
title_full	Opposing roles for striatonigral and striatopallidal neurons in dorsolateral striatum in consolidating new instrumental actions
title_fullStr	Opposing roles for striatonigral and striatopallidal neurons in dorsolateral striatum in consolidating new instrumental actions
title_full_unstemmed	Opposing roles for striatonigral and striatopallidal neurons in dorsolateral striatum in consolidating new instrumental actions
title_sort	opposing roles for striatonigral and striatopallidal neurons in dorsolateral striatum in consolidating new instrumental actions
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/268c60f143c3450aace33229b83ad544
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Opposing roles for striatonigral and striatopallidal neurons in dorsolateral striatum in consolidating new instrumental actions

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