The Shine-Dalgarno sequence of riboswitch-regulated single mRNAs shows ligand-dependent accessibility bursts

In response to intracellular signals, bacterial translational riboswitches embedded in mRNAs can regulate gene expression through inhibition of translation initiation. Here, the authors describe SiM-KARTS, a novel approach for detecting changes in the structure of single RNA molecules in response to...

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Autores principales:	Arlie J. Rinaldi, Paul E. Lund, Mario R. Blanco, Nils G. Walter
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/26903b0deccf4f77ae26a9a3ca7ddc73
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spelling	oai:doaj.org-article:26903b0deccf4f77ae26a9a3ca7ddc732021-12-02T16:58:23ZThe Shine-Dalgarno sequence of riboswitch-regulated single mRNAs shows ligand-dependent accessibility bursts10.1038/ncomms99762041-1723https://doaj.org/article/26903b0deccf4f77ae26a9a3ca7ddc732016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms9976https://doaj.org/toc/2041-1723In response to intracellular signals, bacterial translational riboswitches embedded in mRNAs can regulate gene expression through inhibition of translation initiation. Here, the authors describe SiM-KARTS, a novel approach for detecting changes in the structure of single RNA molecules in response to a ligand.Arlie J. RinaldiPaul E. LundMario R. BlancoNils G. WalterNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Arlie J. Rinaldi Paul E. Lund Mario R. Blanco Nils G. Walter The Shine-Dalgarno sequence of riboswitch-regulated single mRNAs shows ligand-dependent accessibility bursts
description	In response to intracellular signals, bacterial translational riboswitches embedded in mRNAs can regulate gene expression through inhibition of translation initiation. Here, the authors describe SiM-KARTS, a novel approach for detecting changes in the structure of single RNA molecules in response to a ligand.
format	article
author	Arlie J. Rinaldi Paul E. Lund Mario R. Blanco Nils G. Walter
author_facet	Arlie J. Rinaldi Paul E. Lund Mario R. Blanco Nils G. Walter
author_sort	Arlie J. Rinaldi
title	The Shine-Dalgarno sequence of riboswitch-regulated single mRNAs shows ligand-dependent accessibility bursts
title_short	The Shine-Dalgarno sequence of riboswitch-regulated single mRNAs shows ligand-dependent accessibility bursts
title_full	The Shine-Dalgarno sequence of riboswitch-regulated single mRNAs shows ligand-dependent accessibility bursts
title_fullStr	The Shine-Dalgarno sequence of riboswitch-regulated single mRNAs shows ligand-dependent accessibility bursts
title_full_unstemmed	The Shine-Dalgarno sequence of riboswitch-regulated single mRNAs shows ligand-dependent accessibility bursts
title_sort	shine-dalgarno sequence of riboswitch-regulated single mrnas shows ligand-dependent accessibility bursts
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/26903b0deccf4f77ae26a9a3ca7ddc73
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The Shine-Dalgarno sequence of riboswitch-regulated single mRNAs shows ligand-dependent accessibility bursts

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