Extracellular DNA and Type IV Pilus Expression Regulate the Structure and Kinetics of Biofilm Formation by Nontypeable <italic toggle="yes">Haemophilus influenzae</italic>

Extracellular DNA and Type IV Pilus Expression Regulate the Structure and Kinetics of Biofilm Formation by Nontypeable <italic toggle="yes">Haemophilus influenzae</italic>

ABSTRACT Biofilms formed in the middle ear by nontypeable Haemophilus influenzae (NTHI) are central to the chronicity, recurrence, and refractive nature of otitis media (OM). However, mechanisms that underlie the emergence of specific NTHI biofilm structures are unclear. We combined computational an...

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Autores principales: Jayajit Das, Elaine Mokrzan, Vinal Lakhani, Lucia Rosas, Joseph A. Jurcisek, William C. Ray, Lauren O. Bakaletz
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2017
Materias:
agent-based modeling
biofilms
nontypeable Haemophilus influenzae
otitis media
pair correlation
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/269d60c2a31d4aa6abd25f344b89f542
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