Proteome-wide association studies identify biochemical modules associated with a wing-size phenotype in Drosophila melanogaster

How genetic diversity generates complex phenotypes along a continuum remains a fundamental question of biology. Here—applying the emerging SWATH proteomics technology—the authors describe a proteome wide association study (PWAS) of Drosophila wing size and identify functional protein clusters associ...

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Autores principales:	Hirokazu Okada, H. Alexander Ebhardt, Sibylle Chantal Vonesch, Ruedi Aebersold, Ernst Hafen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/26a12fcbe96549b5a1836c3af3924120
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spelling	oai:doaj.org-article:26a12fcbe96549b5a1836c3af39241202021-12-02T14:39:11ZProteome-wide association studies identify biochemical modules associated with a wing-size phenotype in Drosophila melanogaster10.1038/ncomms126492041-1723https://doaj.org/article/26a12fcbe96549b5a1836c3af39241202016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12649https://doaj.org/toc/2041-1723How genetic diversity generates complex phenotypes along a continuum remains a fundamental question of biology. Here—applying the emerging SWATH proteomics technology—the authors describe a proteome wide association study (PWAS) of Drosophila wing size and identify functional protein clusters associated with this trait.Hirokazu OkadaH. Alexander EbhardtSibylle Chantal VoneschRuedi AebersoldErnst HafenNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hirokazu Okada H. Alexander Ebhardt Sibylle Chantal Vonesch Ruedi Aebersold Ernst Hafen Proteome-wide association studies identify biochemical modules associated with a wing-size phenotype in Drosophila melanogaster
description	How genetic diversity generates complex phenotypes along a continuum remains a fundamental question of biology. Here—applying the emerging SWATH proteomics technology—the authors describe a proteome wide association study (PWAS) of Drosophila wing size and identify functional protein clusters associated with this trait.
format	article
author	Hirokazu Okada H. Alexander Ebhardt Sibylle Chantal Vonesch Ruedi Aebersold Ernst Hafen
author_facet	Hirokazu Okada H. Alexander Ebhardt Sibylle Chantal Vonesch Ruedi Aebersold Ernst Hafen
author_sort	Hirokazu Okada
title	Proteome-wide association studies identify biochemical modules associated with a wing-size phenotype in Drosophila melanogaster
title_short	Proteome-wide association studies identify biochemical modules associated with a wing-size phenotype in Drosophila melanogaster
title_full	Proteome-wide association studies identify biochemical modules associated with a wing-size phenotype in Drosophila melanogaster
title_fullStr	Proteome-wide association studies identify biochemical modules associated with a wing-size phenotype in Drosophila melanogaster
title_full_unstemmed	Proteome-wide association studies identify biochemical modules associated with a wing-size phenotype in Drosophila melanogaster
title_sort	proteome-wide association studies identify biochemical modules associated with a wing-size phenotype in drosophila melanogaster
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/26a12fcbe96549b5a1836c3af3924120
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Proteome-wide association studies identify biochemical modules associated with a wing-size phenotype in Drosophila melanogaster

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