Incomplete prophage tolerance by type III-A CRISPR-Cas systems reduces the fitness of lysogenic hosts

CRISPR-Cas systems, such as type III-A CRISPR-Cas, provide an immune mechanism for prokaryotic hosts to resist parasites, including phages. Here, the authors show that maintenance of conditionally tolerant type III-A systems can affect the fitness of Staphylococcus aureus lysogens.

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Autores principales:	Gregory W. Goldberg, Elizabeth A. McMillan, Andrew Varble, Joshua W. Modell, Poulami Samai, Wenyan Jiang, Luciano A. Marraffini
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/26a41b550ed54bc689c612ad1492998b
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spelling	oai:doaj.org-article:26a41b550ed54bc689c612ad1492998b2021-12-02T14:39:05ZIncomplete prophage tolerance by type III-A CRISPR-Cas systems reduces the fitness of lysogenic hosts10.1038/s41467-017-02557-22041-1723https://doaj.org/article/26a41b550ed54bc689c612ad1492998b2018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02557-2https://doaj.org/toc/2041-1723CRISPR-Cas systems, such as type III-A CRISPR-Cas, provide an immune mechanism for prokaryotic hosts to resist parasites, including phages. Here, the authors show that maintenance of conditionally tolerant type III-A systems can affect the fitness of Staphylococcus aureus lysogens.Gregory W. GoldbergElizabeth A. McMillanAndrew VarbleJoshua W. ModellPoulami SamaiWenyan JiangLuciano A. MarraffiniNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Gregory W. Goldberg Elizabeth A. McMillan Andrew Varble Joshua W. Modell Poulami Samai Wenyan Jiang Luciano A. Marraffini Incomplete prophage tolerance by type III-A CRISPR-Cas systems reduces the fitness of lysogenic hosts
description	CRISPR-Cas systems, such as type III-A CRISPR-Cas, provide an immune mechanism for prokaryotic hosts to resist parasites, including phages. Here, the authors show that maintenance of conditionally tolerant type III-A systems can affect the fitness of Staphylococcus aureus lysogens.
format	article
author	Gregory W. Goldberg Elizabeth A. McMillan Andrew Varble Joshua W. Modell Poulami Samai Wenyan Jiang Luciano A. Marraffini
author_facet	Gregory W. Goldberg Elizabeth A. McMillan Andrew Varble Joshua W. Modell Poulami Samai Wenyan Jiang Luciano A. Marraffini
author_sort	Gregory W. Goldberg
title	Incomplete prophage tolerance by type III-A CRISPR-Cas systems reduces the fitness of lysogenic hosts
title_short	Incomplete prophage tolerance by type III-A CRISPR-Cas systems reduces the fitness of lysogenic hosts
title_full	Incomplete prophage tolerance by type III-A CRISPR-Cas systems reduces the fitness of lysogenic hosts
title_fullStr	Incomplete prophage tolerance by type III-A CRISPR-Cas systems reduces the fitness of lysogenic hosts
title_full_unstemmed	Incomplete prophage tolerance by type III-A CRISPR-Cas systems reduces the fitness of lysogenic hosts
title_sort	incomplete prophage tolerance by type iii-a crispr-cas systems reduces the fitness of lysogenic hosts
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/26a41b550ed54bc689c612ad1492998b
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Incomplete prophage tolerance by type III-A CRISPR-Cas systems reduces the fitness of lysogenic hosts

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