Early-life social experience affects offspring DNA methylation and later life stress phenotype

Early social experience can alter epigenetic patterns and stress responses later in life. A study on wild spotted hyenas finds that maternal care and social connections after leaving the den influence DNA methylation and contribute to a developmentally plastic stress response.

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Autores principales: Zachary M. Laubach, Julia R. Greenberg, Julie W. Turner, Tracy M. Montgomery, Malit O. Pioon, Maggie A. Sawdy, Laura Smale, Raymond G. Cavalcante, Karthik R. Padmanabhan, Claudia Lalancette, Bridgett vonHoldt, Christopher D. Faulk, Dana C. Dolinoy, Kay E. Holekamp, Wei Perng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/26a7708842bf456a9e9e486a8e5289da
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spelling oai:doaj.org-article:26a7708842bf456a9e9e486a8e5289da2021-12-02T17:57:04ZEarly-life social experience affects offspring DNA methylation and later life stress phenotype10.1038/s41467-021-24583-x2041-1723https://doaj.org/article/26a7708842bf456a9e9e486a8e5289da2021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24583-xhttps://doaj.org/toc/2041-1723Early social experience can alter epigenetic patterns and stress responses later in life. A study on wild spotted hyenas finds that maternal care and social connections after leaving the den influence DNA methylation and contribute to a developmentally plastic stress response.Zachary M. LaubachJulia R. GreenbergJulie W. TurnerTracy M. MontgomeryMalit O. PioonMaggie A. SawdyLaura SmaleRaymond G. CavalcanteKarthik R. PadmanabhanClaudia LalancetteBridgett vonHoldtChristopher D. FaulkDana C. DolinoyKay E. HolekampWei PerngNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Zachary M. Laubach
Julia R. Greenberg
Julie W. Turner
Tracy M. Montgomery
Malit O. Pioon
Maggie A. Sawdy
Laura Smale
Raymond G. Cavalcante
Karthik R. Padmanabhan
Claudia Lalancette
Bridgett vonHoldt
Christopher D. Faulk
Dana C. Dolinoy
Kay E. Holekamp
Wei Perng
Early-life social experience affects offspring DNA methylation and later life stress phenotype
description Early social experience can alter epigenetic patterns and stress responses later in life. A study on wild spotted hyenas finds that maternal care and social connections after leaving the den influence DNA methylation and contribute to a developmentally plastic stress response.
format article
author Zachary M. Laubach
Julia R. Greenberg
Julie W. Turner
Tracy M. Montgomery
Malit O. Pioon
Maggie A. Sawdy
Laura Smale
Raymond G. Cavalcante
Karthik R. Padmanabhan
Claudia Lalancette
Bridgett vonHoldt
Christopher D. Faulk
Dana C. Dolinoy
Kay E. Holekamp
Wei Perng
author_facet Zachary M. Laubach
Julia R. Greenberg
Julie W. Turner
Tracy M. Montgomery
Malit O. Pioon
Maggie A. Sawdy
Laura Smale
Raymond G. Cavalcante
Karthik R. Padmanabhan
Claudia Lalancette
Bridgett vonHoldt
Christopher D. Faulk
Dana C. Dolinoy
Kay E. Holekamp
Wei Perng
author_sort Zachary M. Laubach
title Early-life social experience affects offspring DNA methylation and later life stress phenotype
title_short Early-life social experience affects offspring DNA methylation and later life stress phenotype
title_full Early-life social experience affects offspring DNA methylation and later life stress phenotype
title_fullStr Early-life social experience affects offspring DNA methylation and later life stress phenotype
title_full_unstemmed Early-life social experience affects offspring DNA methylation and later life stress phenotype
title_sort early-life social experience affects offspring dna methylation and later life stress phenotype
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/26a7708842bf456a9e9e486a8e5289da
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