T cell specific Cxcr5 deficiency prevents rheumatoid arthritis

T cell specific Cxcr5 deficiency prevents rheumatoid arthritis

Abstract The chemokine receptor CXCR5 is primarily expressed on B cells and Tfh cells and facilitates their migration towards B cell follicles. In the present study we investigated the role of the CXCL13/CXCR5 axis in the pathogenesis of rheumatoid arthritis (RA) and specifically addressed the impac...

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Autores principales: Georgios L. Moschovakis, Anja Bubke, Michaela Friedrichsen, Christine S. Falk, Regina Feederle, Reinhold Förster
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/26ad5b1349cb4222bb959cc284c84ee8
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