Cellular and Molecular Mechanism of Traditional Chinese Medicine on Ventricular Remodeling

Ventricular remodeling is related to the renin-angiotensin-aldosterone system, immune system, and various cytokines involved in inflammation, apoptosis, and cell signal regulation. Accumulated studies have shown that traditional Chinese medicine can significantly inhibit the process of ventricular r...

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Autores principales:	Yong-Chun Zhu, Bo Liang, Ning Gu
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	ventricular remodeling traditional Chinese medicine mechanism cardiovascular disease review Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/26ae18a813ea402787f5b9829d665808
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id	oai:doaj.org-article:26ae18a813ea402787f5b9829d665808
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spelling	oai:doaj.org-article:26ae18a813ea402787f5b9829d6658082021-12-01T22:23:47ZCellular and Molecular Mechanism of Traditional Chinese Medicine on Ventricular Remodeling2297-055X10.3389/fcvm.2021.753095https://doaj.org/article/26ae18a813ea402787f5b9829d6658082021-12-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fcvm.2021.753095/fullhttps://doaj.org/toc/2297-055XVentricular remodeling is related to the renin-angiotensin-aldosterone system, immune system, and various cytokines involved in inflammation, apoptosis, and cell signal regulation. Accumulated studies have shown that traditional Chinese medicine can significantly inhibit the process of ventricular remodeling, which may be related to the mechanism mentioned above. Here, we conducted a system overview to critically review the cellular and molecular mechanism of traditional Chinese medicine on ventricular remodeling. We mainly searched PubMed for basic research about the anti-ventricular remodeling of traditional Chinese medicine in 5 recent years, and then objectively summarized these researches. We included more than 25 kinds of Chinese herbal medicines including Qi-Li-Qian-Xin, Qi-Shen-Yi-Qi Pill, Xin-Ji-Er-Kang Formula, and Yi-Qi-Wen-Yang Decoction, and found that they can inhibit ventricular remodeling effectively through multi-components and multi-action targets, which are promoting the clinical application of traditional Chinese medicine.Yong-Chun ZhuBo LiangNing GuFrontiers Media S.A.articleventricular remodelingtraditional Chinese medicinemechanismcardiovascular diseasereviewDiseases of the circulatory (Cardiovascular) systemRC666-701ENFrontiers in Cardiovascular Medicine, Vol 8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	ventricular remodeling traditional Chinese medicine mechanism cardiovascular disease review Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	ventricular remodeling traditional Chinese medicine mechanism cardiovascular disease review Diseases of the circulatory (Cardiovascular) system RC666-701 Yong-Chun Zhu Bo Liang Ning Gu Cellular and Molecular Mechanism of Traditional Chinese Medicine on Ventricular Remodeling
description	Ventricular remodeling is related to the renin-angiotensin-aldosterone system, immune system, and various cytokines involved in inflammation, apoptosis, and cell signal regulation. Accumulated studies have shown that traditional Chinese medicine can significantly inhibit the process of ventricular remodeling, which may be related to the mechanism mentioned above. Here, we conducted a system overview to critically review the cellular and molecular mechanism of traditional Chinese medicine on ventricular remodeling. We mainly searched PubMed for basic research about the anti-ventricular remodeling of traditional Chinese medicine in 5 recent years, and then objectively summarized these researches. We included more than 25 kinds of Chinese herbal medicines including Qi-Li-Qian-Xin, Qi-Shen-Yi-Qi Pill, Xin-Ji-Er-Kang Formula, and Yi-Qi-Wen-Yang Decoction, and found that they can inhibit ventricular remodeling effectively through multi-components and multi-action targets, which are promoting the clinical application of traditional Chinese medicine.
format	article
author	Yong-Chun Zhu Bo Liang Ning Gu
author_facet	Yong-Chun Zhu Bo Liang Ning Gu
author_sort	Yong-Chun Zhu
title	Cellular and Molecular Mechanism of Traditional Chinese Medicine on Ventricular Remodeling
title_short	Cellular and Molecular Mechanism of Traditional Chinese Medicine on Ventricular Remodeling
title_full	Cellular and Molecular Mechanism of Traditional Chinese Medicine on Ventricular Remodeling
title_fullStr	Cellular and Molecular Mechanism of Traditional Chinese Medicine on Ventricular Remodeling
title_full_unstemmed	Cellular and Molecular Mechanism of Traditional Chinese Medicine on Ventricular Remodeling
title_sort	cellular and molecular mechanism of traditional chinese medicine on ventricular remodeling
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/26ae18a813ea402787f5b9829d665808
work_keys_str_mv	AT yongchunzhu cellularandmolecularmechanismoftraditionalchinesemedicineonventricularremodeling AT boliang cellularandmolecularmechanismoftraditionalchinesemedicineonventricularremodeling AT ninggu cellularandmolecularmechanismoftraditionalchinesemedicineonventricularremodeling
_version_	1718404090001620992

Cellular and Molecular Mechanism of Traditional Chinese Medicine on Ventricular Remodeling

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