Interaction of the cotranslational Hsp70 Ssb with ribosomal proteins and rRNA depends on its lid domain

In yeast, the heterodimeric ribosome-associated complex (RAC) acts in concert with the Hsp70 protein Ssb, forming a unique chaperone triad. Here the authors use structural and biochemical approaches to shed light on how translation and folding are coupled in eukaryotes.

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Autores principales:	Andrea Gumiero, Charlotte Conz, Genís Valentín Gesé, Ying Zhang, Felix Alexander Weyer, Karine Lapouge, Julia Kappes, Ulrike von Plehwe, Géza Schermann, Edith Fitzke, Tina Wölfle, Tamás Fischer, Sabine Rospert, Irmgard Sinning
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/26b640aed56d4e9cb16591f7ffb42612
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spelling	oai:doaj.org-article:26b640aed56d4e9cb16591f7ffb426122021-12-02T17:32:23ZInteraction of the cotranslational Hsp70 Ssb with ribosomal proteins and rRNA depends on its lid domain10.1038/ncomms135632041-1723https://doaj.org/article/26b640aed56d4e9cb16591f7ffb426122016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13563https://doaj.org/toc/2041-1723In yeast, the heterodimeric ribosome-associated complex (RAC) acts in concert with the Hsp70 protein Ssb, forming a unique chaperone triad. Here the authors use structural and biochemical approaches to shed light on how translation and folding are coupled in eukaryotes.Andrea GumieroCharlotte ConzGenís Valentín GeséYing ZhangFelix Alexander WeyerKarine LapougeJulia KappesUlrike von PlehweGéza SchermannEdith FitzkeTina WölfleTamás FischerSabine RospertIrmgard SinningNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Andrea Gumiero Charlotte Conz Genís Valentín Gesé Ying Zhang Felix Alexander Weyer Karine Lapouge Julia Kappes Ulrike von Plehwe Géza Schermann Edith Fitzke Tina Wölfle Tamás Fischer Sabine Rospert Irmgard Sinning Interaction of the cotranslational Hsp70 Ssb with ribosomal proteins and rRNA depends on its lid domain
description	In yeast, the heterodimeric ribosome-associated complex (RAC) acts in concert with the Hsp70 protein Ssb, forming a unique chaperone triad. Here the authors use structural and biochemical approaches to shed light on how translation and folding are coupled in eukaryotes.
format	article
author	Andrea Gumiero Charlotte Conz Genís Valentín Gesé Ying Zhang Felix Alexander Weyer Karine Lapouge Julia Kappes Ulrike von Plehwe Géza Schermann Edith Fitzke Tina Wölfle Tamás Fischer Sabine Rospert Irmgard Sinning
author_facet	Andrea Gumiero Charlotte Conz Genís Valentín Gesé Ying Zhang Felix Alexander Weyer Karine Lapouge Julia Kappes Ulrike von Plehwe Géza Schermann Edith Fitzke Tina Wölfle Tamás Fischer Sabine Rospert Irmgard Sinning
author_sort	Andrea Gumiero
title	Interaction of the cotranslational Hsp70 Ssb with ribosomal proteins and rRNA depends on its lid domain
title_short	Interaction of the cotranslational Hsp70 Ssb with ribosomal proteins and rRNA depends on its lid domain
title_full	Interaction of the cotranslational Hsp70 Ssb with ribosomal proteins and rRNA depends on its lid domain
title_fullStr	Interaction of the cotranslational Hsp70 Ssb with ribosomal proteins and rRNA depends on its lid domain
title_full_unstemmed	Interaction of the cotranslational Hsp70 Ssb with ribosomal proteins and rRNA depends on its lid domain
title_sort	interaction of the cotranslational hsp70 ssb with ribosomal proteins and rrna depends on its lid domain
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/26b640aed56d4e9cb16591f7ffb42612
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Interaction of the cotranslational Hsp70 Ssb with ribosomal proteins and rRNA depends on its lid domain

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