Feline Demodicosis Case Report—First Molecular Characterization of Demodex Mites in Romania

Cat demodicosis is uncommon to rare, and is caused by Demodex cati, Demodex gatoi and another unnamed species. The investigated patient was a mix-breed, 10-year-old feline with no dermatological history. Alopecia, erythema, minor erosions and ulcerations and cru...

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Autores principales:	Marius Stelian Ilie, Mirela Imre, Simona Giubega, Iasmina Luca, Tiana Florea, Sorin Morariu
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	cat PCR <i>Demodex cati</i> Romania fluralaner moxidectin Medicine R
Acceso en línea:	https://doaj.org/article/26bff5903447401db1349a3eb3af56d7
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spelling	oai:doaj.org-article:26bff5903447401db1349a3eb3af56d72021-11-25T18:38:33ZFeline Demodicosis Case Report—First Molecular Characterization of <i>Demodex</i> Mites in Romania10.3390/pathogens101114742076-0817https://doaj.org/article/26bff5903447401db1349a3eb3af56d72021-11-01T00:00:00Zhttps://www.mdpi.com/2076-0817/10/11/1474https://doaj.org/toc/2076-0817Cat demodicosis is uncommon to rare, and is caused by <i>Demodex cati</i>, <i>Demodex gatoi</i> and another unnamed species. The investigated patient was a mix-breed, 10-year-old feline with no dermatological history. Alopecia, erythema, minor erosions and ulcerations and crusts, associated with pruritus and self-trauma, were observed on the head. Dark, agglutinated cerumen was also present in the external ear canal. The agent causing the skin condition in the feline patient was identified as being a <i>Demodex</i> genus mite, based on the specific, morphological characteristics noticed upon the microscopic examination of deep skin scrapes. Biological samples were collected from the patient with to perform a PCR assay for clear species-determination and morphological assessment. PCR amplification of DNA extracted from the <i>Demodex</i> mites produced a single band of ~330 bp, indicating the presence of the <i>D. cati</i> species. The acaricidal treatment consisted of topical treatment using a fluralaner and moxidectin-based spot-on. Upon follow-up appointments, scheduled three times at a monthly interval, the patient failed to provide a positive result upon deep skin scrapes. The negative scrapes were also accompanied by the complete resolution of the existing lesions. In conclusion, this is the first molecular study to highlight the presence of <i>Demodex cati</i> within the feline population of Romania, and the fluralaner-moxidectin spot-on therapy has led to a complete recovery of the feline patient affected by feline demodicosis.Marius Stelian IlieMirela ImreSimona GiubegaIasmina LucaTiana FloreaSorin MorariuMDPI AGarticlecatPCR<i>Demodex cati</i>RomaniafluralanermoxidectinMedicineRENPathogens, Vol 10, Iss 1474, p 1474 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	cat PCR <i>Demodex cati</i> Romania fluralaner moxidectin Medicine R
spellingShingle	cat PCR <i>Demodex cati</i> Romania fluralaner moxidectin Medicine R Marius Stelian Ilie Mirela Imre Simona Giubega Iasmina Luca Tiana Florea Sorin Morariu Feline Demodicosis Case Report—First Molecular Characterization of <i>Demodex</i> Mites in Romania
description	Cat demodicosis is uncommon to rare, and is caused by <i>Demodex cati</i>, <i>Demodex gatoi</i> and another unnamed species. The investigated patient was a mix-breed, 10-year-old feline with no dermatological history. Alopecia, erythema, minor erosions and ulcerations and crusts, associated with pruritus and self-trauma, were observed on the head. Dark, agglutinated cerumen was also present in the external ear canal. The agent causing the skin condition in the feline patient was identified as being a <i>Demodex</i> genus mite, based on the specific, morphological characteristics noticed upon the microscopic examination of deep skin scrapes. Biological samples were collected from the patient with to perform a PCR assay for clear species-determination and morphological assessment. PCR amplification of DNA extracted from the <i>Demodex</i> mites produced a single band of ~330 bp, indicating the presence of the <i>D. cati</i> species. The acaricidal treatment consisted of topical treatment using a fluralaner and moxidectin-based spot-on. Upon follow-up appointments, scheduled three times at a monthly interval, the patient failed to provide a positive result upon deep skin scrapes. The negative scrapes were also accompanied by the complete resolution of the existing lesions. In conclusion, this is the first molecular study to highlight the presence of <i>Demodex cati</i> within the feline population of Romania, and the fluralaner-moxidectin spot-on therapy has led to a complete recovery of the feline patient affected by feline demodicosis.
format	article
author	Marius Stelian Ilie Mirela Imre Simona Giubega Iasmina Luca Tiana Florea Sorin Morariu
author_facet	Marius Stelian Ilie Mirela Imre Simona Giubega Iasmina Luca Tiana Florea Sorin Morariu
author_sort	Marius Stelian Ilie
title	Feline Demodicosis Case Report—First Molecular Characterization of <i>Demodex</i> Mites in Romania
title_short	Feline Demodicosis Case Report—First Molecular Characterization of <i>Demodex</i> Mites in Romania
title_full	Feline Demodicosis Case Report—First Molecular Characterization of <i>Demodex</i> Mites in Romania
title_fullStr	Feline Demodicosis Case Report—First Molecular Characterization of <i>Demodex</i> Mites in Romania
title_full_unstemmed	Feline Demodicosis Case Report—First Molecular Characterization of <i>Demodex</i> Mites in Romania
title_sort	feline demodicosis case report—first molecular characterization of <i>demodex</i> mites in romania
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/26bff5903447401db1349a3eb3af56d7
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Feline Demodicosis Case Report—First Molecular Characterization of <i>Demodex</i> Mites in Romania

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