Structural basis of Gip1 for cytosolic sequestration of G protein in wide-range chemotaxis
Gip1 sequesters heterotrimeric G proteins in the cytosolic pool which regulates G protein-coupled receptor signalling for eukaryotic chemotaxis. Here the authors provide the crystal structure of Gip1's G protein-binding region and show that mutations in this region lead to G protein sequestrati...
Guardado en:
Autores principales: | Takero Miyagawa, Hiroyasu Koteishi, Yoichiro Kamimura, Yukihiro Miyanaga, Kohei Takeshita, Atsushi Nakagawa, Masahiro Ueda |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/26c4cb29ce9e49fc94c2bac5a504119a |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Cytosolic sequestration of the vitamin D receptor as a therapeutic option for vitamin D-induced hypercalcemia
por: Daniela Rovito, et al.
Publicado: (2020) -
GIP_HUMAN[22–51] is a new proatherogenic peptide identified by native plasma peptidomics
por: Tsuguto Masaki, et al.
Publicado: (2021) -
Enhancing T Cell Chemotaxis and Infiltration in Glioblastoma
por: Kirit Singh, et al.
Publicado: (2021) -
Inverted signaling by bacterial chemotaxis receptors
por: Shuangyu Bi, et al.
Publicado: (2018) -
Clinical case of lung sequestration
por: V. N. Stalmakhovich, et al.
Publicado: (2013)