Dysfunctional TRPM8 signalling in the vascular response to environmental cold in ageing
Ageing is associated with increased vulnerability to environmental cold exposure. Previously, we identified the role of the cold-sensitive transient receptor potential (TRP) A1, M8 receptors as vascular cold sensors in mouse skin. We hypothesised that this dynamic cold-sensor system may become dysfu...
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Autores principales: | Dibesh Thapa, Joäo de Sousa Valente, Brentton Barrett, Matthew John Smith, Fulye Argunhan, Sheng Y Lee, Sofya Nikitochkina, Xenia Kodji, Susan D Brain |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
eLife Sciences Publications Ltd
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/26ce2891ff7b4b918ed2630701c56e1e |
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