Mapping the chromatin landscape and Blimp1 transcriptional targets that regulate trophoblast differentiation

Abstract Trophoblast stem cells (TSCs) give rise to specialized cell types within the placenta. However, the regulatory mechanisms that guide trophoblast cell fate decisions during placenta development remain ill defined. Here we exploited ATAC-seq and transcriptional profiling strategies to describ...

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Autores principales: Andrew C. Nelson, Arne W. Mould, Elizabeth K. Bikoff, Elizabeth J. Robertson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/26d028b01be84c588d0195e0202b97a3
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