Leisure-time, occupational, and commuting physical activity and the risk of chronic kidney disease in a working population

Abstract Physical activity has been linked to a lower risk of chronic kidney disease (CKD); however, evidence on the relationship between domain-specific physical activity and CKD is scarce. This study aimed to examine the risk of CKD in relation to leisure-time, occupational, and commuting physical...

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Autores principales: Shohei Yamamoto, Yosuke Inoue, Keisuke Kuwahara, Takako Miki, Tohru Nakagawa, Toru Honda, Shuichiro Yamamoto, Takeshi Hayashi, Tetsuya Mizoue
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/26d0f1466de84072bab6e0c4d659f91b
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spelling oai:doaj.org-article:26d0f1466de84072bab6e0c4d659f91b2021-12-02T14:58:20ZLeisure-time, occupational, and commuting physical activity and the risk of chronic kidney disease in a working population10.1038/s41598-021-91525-42045-2322https://doaj.org/article/26d0f1466de84072bab6e0c4d659f91b2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-91525-4https://doaj.org/toc/2045-2322Abstract Physical activity has been linked to a lower risk of chronic kidney disease (CKD); however, evidence on the relationship between domain-specific physical activity and CKD is scarce. This study aimed to examine the risk of CKD in relation to leisure-time, occupational, and commuting physical activities in a large occupational cohort in Japan. Participants were 17,331 workers (20–65 years old) without CKD and were followed-up for a maximum period of 13 years. Incident CKD was defined as an estimated glomerular filtration rate of < 60 mL/min/1.73 m2 and/or proteinuria determined using the dipstick test. The Cox proportional hazards models were used to examine the associations. During 147,752 person-years of follow-up, 4013 participants developed CKD. Workers who were standing or walking at work and those who were fairly active at work had adjusted hazard ratios of 0.88 (95% confidence interval 0.86–0.96) and 0.89 (95% confidence interval 0.78–1.02), respectively, for developing CKD than sedentary workers. Leisure-time physical activity and walking for commute were not associated with CKD risk. Our findings suggest that occupational, but not leisure-time and commuting physical activities, is associated with a lower CKD risk.Shohei YamamotoYosuke InoueKeisuke KuwaharaTakako MikiTohru NakagawaToru HondaShuichiro YamamotoTakeshi HayashiTetsuya MizoueNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Shohei Yamamoto
Yosuke Inoue
Keisuke Kuwahara
Takako Miki
Tohru Nakagawa
Toru Honda
Shuichiro Yamamoto
Takeshi Hayashi
Tetsuya Mizoue
Leisure-time, occupational, and commuting physical activity and the risk of chronic kidney disease in a working population
description Abstract Physical activity has been linked to a lower risk of chronic kidney disease (CKD); however, evidence on the relationship between domain-specific physical activity and CKD is scarce. This study aimed to examine the risk of CKD in relation to leisure-time, occupational, and commuting physical activities in a large occupational cohort in Japan. Participants were 17,331 workers (20–65 years old) without CKD and were followed-up for a maximum period of 13 years. Incident CKD was defined as an estimated glomerular filtration rate of < 60 mL/min/1.73 m2 and/or proteinuria determined using the dipstick test. The Cox proportional hazards models were used to examine the associations. During 147,752 person-years of follow-up, 4013 participants developed CKD. Workers who were standing or walking at work and those who were fairly active at work had adjusted hazard ratios of 0.88 (95% confidence interval 0.86–0.96) and 0.89 (95% confidence interval 0.78–1.02), respectively, for developing CKD than sedentary workers. Leisure-time physical activity and walking for commute were not associated with CKD risk. Our findings suggest that occupational, but not leisure-time and commuting physical activities, is associated with a lower CKD risk.
format article
author Shohei Yamamoto
Yosuke Inoue
Keisuke Kuwahara
Takako Miki
Tohru Nakagawa
Toru Honda
Shuichiro Yamamoto
Takeshi Hayashi
Tetsuya Mizoue
author_facet Shohei Yamamoto
Yosuke Inoue
Keisuke Kuwahara
Takako Miki
Tohru Nakagawa
Toru Honda
Shuichiro Yamamoto
Takeshi Hayashi
Tetsuya Mizoue
author_sort Shohei Yamamoto
title Leisure-time, occupational, and commuting physical activity and the risk of chronic kidney disease in a working population
title_short Leisure-time, occupational, and commuting physical activity and the risk of chronic kidney disease in a working population
title_full Leisure-time, occupational, and commuting physical activity and the risk of chronic kidney disease in a working population
title_fullStr Leisure-time, occupational, and commuting physical activity and the risk of chronic kidney disease in a working population
title_full_unstemmed Leisure-time, occupational, and commuting physical activity and the risk of chronic kidney disease in a working population
title_sort leisure-time, occupational, and commuting physical activity and the risk of chronic kidney disease in a working population
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/26d0f1466de84072bab6e0c4d659f91b
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