Macrophages orchestrate breast cancer early dissemination and metastasis

Early dissemination of cancer cells has been reported to occur in certain breast cancer models. Here the authors show that intra-epithelial macrophages in the early pre-cancer lesions drive early cancer cell dissemination through Wnt-1 secretion and that such events impact the later development of m...

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Autores principales:	Nina Linde, Maria Casanova-Acebes, Maria Soledad Sosa, Arthur Mortha, Adeeb Rahman, Eduardo Farias, Kathryn Harper, Ethan Tardio, Ivan Reyes Torres, Joan Jones, John Condeelis, Miriam Merad, Julio A. Aguirre-Ghiso
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/26d917dd15e34f92be68de21ef6a76c2
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spelling	oai:doaj.org-article:26d917dd15e34f92be68de21ef6a76c22021-12-02T14:38:50ZMacrophages orchestrate breast cancer early dissemination and metastasis10.1038/s41467-017-02481-52041-1723https://doaj.org/article/26d917dd15e34f92be68de21ef6a76c22018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02481-5https://doaj.org/toc/2041-1723Early dissemination of cancer cells has been reported to occur in certain breast cancer models. Here the authors show that intra-epithelial macrophages in the early pre-cancer lesions drive early cancer cell dissemination through Wnt-1 secretion and that such events impact the later development of metastasis.Nina LindeMaria Casanova-AcebesMaria Soledad SosaArthur MorthaAdeeb RahmanEduardo FariasKathryn HarperEthan TardioIvan Reyes TorresJoan JonesJohn CondeelisMiriam MeradJulio A. Aguirre-GhisoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nina Linde Maria Casanova-Acebes Maria Soledad Sosa Arthur Mortha Adeeb Rahman Eduardo Farias Kathryn Harper Ethan Tardio Ivan Reyes Torres Joan Jones John Condeelis Miriam Merad Julio A. Aguirre-Ghiso Macrophages orchestrate breast cancer early dissemination and metastasis
description	Early dissemination of cancer cells has been reported to occur in certain breast cancer models. Here the authors show that intra-epithelial macrophages in the early pre-cancer lesions drive early cancer cell dissemination through Wnt-1 secretion and that such events impact the later development of metastasis.
format	article
author	Nina Linde Maria Casanova-Acebes Maria Soledad Sosa Arthur Mortha Adeeb Rahman Eduardo Farias Kathryn Harper Ethan Tardio Ivan Reyes Torres Joan Jones John Condeelis Miriam Merad Julio A. Aguirre-Ghiso
author_facet	Nina Linde Maria Casanova-Acebes Maria Soledad Sosa Arthur Mortha Adeeb Rahman Eduardo Farias Kathryn Harper Ethan Tardio Ivan Reyes Torres Joan Jones John Condeelis Miriam Merad Julio A. Aguirre-Ghiso
author_sort	Nina Linde
title	Macrophages orchestrate breast cancer early dissemination and metastasis
title_short	Macrophages orchestrate breast cancer early dissemination and metastasis
title_full	Macrophages orchestrate breast cancer early dissemination and metastasis
title_fullStr	Macrophages orchestrate breast cancer early dissemination and metastasis
title_full_unstemmed	Macrophages orchestrate breast cancer early dissemination and metastasis
title_sort	macrophages orchestrate breast cancer early dissemination and metastasis
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/26d917dd15e34f92be68de21ef6a76c2
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Macrophages orchestrate breast cancer early dissemination and metastasis

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