Synergized regulation of NK cell education by NKG2A and specific Ly49 family members

MHC-I-induced signalling of various natural killer (NK) inhibitory receptors is critical for regulation NK cell education, but clear genetic evidence is still lacking. Here the authors generate multiple lines of mice differentially deficient in Ly49 family and/or NKG2A NK receptors, and find that se...

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Autores principales: Xiaoqian Zhang, Jin Feng, Shasha Chen, Haoyan Yang, Zhongjun Dong
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/26d9a5825ab940e5a49b115dd12d8fe3
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