EXPRESSION LEVELS OF SOME ADHESION MOLECULES IN THE INTACT AND UV-IRRADIATED Т-LYMPHOCYTES FROM HUMAN BLOOD

Abstract. While employing an enzyme linked immunosorbent assay, it was shown that UV-sensitivity is different for various adhesion molecules (CD2, CD11a and CD29) at the membranes of T-lymphocytes. Relative photoresistance of CD2 and CD11a antigens to UV irradiation was established at the doses rang...

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Autores principales:	V. G. Artyukhov, O. V. Putintseva, S. M. Dubova
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	adhesion molecules expression photosensitivity elisa Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/26da6b08e1d84d16bfb60519e767d322
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spelling	oai:doaj.org-article:26da6b08e1d84d16bfb60519e767d3222021-11-18T08:03:38ZEXPRESSION LEVELS OF SOME ADHESION MOLECULES IN THE INTACT AND UV-IRRADIATED Т-LYMPHOCYTES FROM HUMAN BLOOD1563-06252313-741X10.15789/1563-0625-2009-1-79-84https://doaj.org/article/26da6b08e1d84d16bfb60519e767d3222014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/212https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. While employing an enzyme linked immunosorbent assay, it was shown that UV-sensitivity is different for various adhesion molecules (CD2, CD11a and CD29) at the membranes of T-lymphocytes. Relative photoresistance of CD2 and CD11a antigens to UV irradiation was established at the doses range of 151 to 906 J/m2, a large dose of UV-iradiation (1359 J/m2) exerted a suppressive effect upon their expression level. An immunomodulatory action of UV-radiation was revealed upon expression of CD29 transmembrane protein by T-cells. A dependence between amino acid structure and photosensitivity of CD2, CD11a and CD29 antigens of T lymphocytes is analyzed and discussed.V. G. ArtyukhovO. V. PutintsevaS. M. DubovaSPb RAACIarticleadhesion moleculesexpressionphotosensitivityelisaImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 11, Iss 1, Pp 79-84 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	adhesion molecules expression photosensitivity elisa Immunologic diseases. Allergy RC581-607
spellingShingle	adhesion molecules expression photosensitivity elisa Immunologic diseases. Allergy RC581-607 V. G. Artyukhov O. V. Putintseva S. M. Dubova EXPRESSION LEVELS OF SOME ADHESION MOLECULES IN THE INTACT AND UV-IRRADIATED Т-LYMPHOCYTES FROM HUMAN BLOOD
description	Abstract. While employing an enzyme linked immunosorbent assay, it was shown that UV-sensitivity is different for various adhesion molecules (CD2, CD11a and CD29) at the membranes of T-lymphocytes. Relative photoresistance of CD2 and CD11a antigens to UV irradiation was established at the doses range of 151 to 906 J/m2, a large dose of UV-iradiation (1359 J/m2) exerted a suppressive effect upon their expression level. An immunomodulatory action of UV-radiation was revealed upon expression of CD29 transmembrane protein by T-cells. A dependence between amino acid structure and photosensitivity of CD2, CD11a and CD29 antigens of T lymphocytes is analyzed and discussed.
format	article
author	V. G. Artyukhov O. V. Putintseva S. M. Dubova
author_facet	V. G. Artyukhov O. V. Putintseva S. M. Dubova
author_sort	V. G. Artyukhov
title	EXPRESSION LEVELS OF SOME ADHESION MOLECULES IN THE INTACT AND UV-IRRADIATED Т-LYMPHOCYTES FROM HUMAN BLOOD
title_short	EXPRESSION LEVELS OF SOME ADHESION MOLECULES IN THE INTACT AND UV-IRRADIATED Т-LYMPHOCYTES FROM HUMAN BLOOD
title_full	EXPRESSION LEVELS OF SOME ADHESION MOLECULES IN THE INTACT AND UV-IRRADIATED Т-LYMPHOCYTES FROM HUMAN BLOOD
title_fullStr	EXPRESSION LEVELS OF SOME ADHESION MOLECULES IN THE INTACT AND UV-IRRADIATED Т-LYMPHOCYTES FROM HUMAN BLOOD
title_full_unstemmed	EXPRESSION LEVELS OF SOME ADHESION MOLECULES IN THE INTACT AND UV-IRRADIATED Т-LYMPHOCYTES FROM HUMAN BLOOD
title_sort	expression levels of some adhesion molecules in the intact and uv-irradiated т-lymphocytes from human blood
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/26da6b08e1d84d16bfb60519e767d322
work_keys_str_mv	AT vgartyukhov expressionlevelsofsomeadhesionmoleculesintheintactanduvirradiatedtlymphocytesfromhumanblood AT ovputintseva expressionlevelsofsomeadhesionmoleculesintheintactanduvirradiatedtlymphocytesfromhumanblood AT smdubova expressionlevelsofsomeadhesionmoleculesintheintactanduvirradiatedtlymphocytesfromhumanblood
_version_	1718422531821535232

EXPRESSION LEVELS OF SOME ADHESION MOLECULES IN THE INTACT AND UV-IRRADIATED Т-LYMPHOCYTES FROM HUMAN BLOOD

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