Histone deacetylase HDA-1 modulates mitochondrial stress response and longevity
Caenorhabditis elegans responds to mitochondrial stress by activating the mitochondrial unfolded protein response (UPRmt). Here the authors show that HDA-1, the C. elegans ortholog of mammalian histone deacetylase (HDAC), coordinates with the genome organizer DVE-1 to activate UPRmt and modulate mit...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2020
|
| Subjects: | |
| Online Access: | https://doaj.org/article/26de9ce408b94ac48ae0d0bb672b22eb |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|