Impact of functional synapse clusters on neuronal response selectivity

The formation of functional synaptic clusters (FSCs) and their impact on somatic membrane potential (sVm) in vivo are poorly understood. Here, the authors develop a computational approach to show that FSCs have to form via local rather than global plasticity and be moderately large to impact sVm.

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Auteurs principaux:	Balázs B. Ujfalussy, Judit K. Makara
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2020
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/26deb0c6b32c4646ba6e041777e4dbff
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id	oai:doaj.org-article:26deb0c6b32c4646ba6e041777e4dbff
record_format	dspace
spelling	oai:doaj.org-article:26deb0c6b32c4646ba6e041777e4dbff2021-12-02T14:40:29ZImpact of functional synapse clusters on neuronal response selectivity10.1038/s41467-020-15147-62041-1723https://doaj.org/article/26deb0c6b32c4646ba6e041777e4dbff2020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15147-6https://doaj.org/toc/2041-1723The formation of functional synaptic clusters (FSCs) and their impact on somatic membrane potential (sVm) in vivo are poorly understood. Here, the authors develop a computational approach to show that FSCs have to form via local rather than global plasticity and be moderately large to impact sVm.Balázs B. UjfalussyJudit K. MakaraNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Balázs B. Ujfalussy Judit K. Makara Impact of functional synapse clusters on neuronal response selectivity
description	The formation of functional synaptic clusters (FSCs) and their impact on somatic membrane potential (sVm) in vivo are poorly understood. Here, the authors develop a computational approach to show that FSCs have to form via local rather than global plasticity and be moderately large to impact sVm.
format	article
author	Balázs B. Ujfalussy Judit K. Makara
author_facet	Balázs B. Ujfalussy Judit K. Makara
author_sort	Balázs B. Ujfalussy
title	Impact of functional synapse clusters on neuronal response selectivity
title_short	Impact of functional synapse clusters on neuronal response selectivity
title_full	Impact of functional synapse clusters on neuronal response selectivity
title_fullStr	Impact of functional synapse clusters on neuronal response selectivity
title_full_unstemmed	Impact of functional synapse clusters on neuronal response selectivity
title_sort	impact of functional synapse clusters on neuronal response selectivity
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/26deb0c6b32c4646ba6e041777e4dbff
work_keys_str_mv	AT balazsbujfalussy impactoffunctionalsynapseclustersonneuronalresponseselectivity AT juditkmakara impactoffunctionalsynapseclustersonneuronalresponseselectivity
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Impact of functional synapse clusters on neuronal response selectivity

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