Impact of functional synapse clusters on neuronal response selectivity

The formation of functional synaptic clusters (FSCs) and their impact on somatic membrane potential (sVm) in vivo are poorly understood. Here, the authors develop a computational approach to show that FSCs have to form via local rather than global plasticity and be moderately large to impact sVm.

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Autores principales: Balázs B. Ujfalussy, Judit K. Makara
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/26deb0c6b32c4646ba6e041777e4dbff
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spelling oai:doaj.org-article:26deb0c6b32c4646ba6e041777e4dbff2021-12-02T14:40:29ZImpact of functional synapse clusters on neuronal response selectivity10.1038/s41467-020-15147-62041-1723https://doaj.org/article/26deb0c6b32c4646ba6e041777e4dbff2020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15147-6https://doaj.org/toc/2041-1723The formation of functional synaptic clusters (FSCs) and their impact on somatic membrane potential (sVm) in vivo are poorly understood. Here, the authors develop a computational approach to show that FSCs have to form via local rather than global plasticity and be moderately large to impact sVm.Balázs B. UjfalussyJudit K. MakaraNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Balázs B. Ujfalussy
Judit K. Makara
Impact of functional synapse clusters on neuronal response selectivity
description The formation of functional synaptic clusters (FSCs) and their impact on somatic membrane potential (sVm) in vivo are poorly understood. Here, the authors develop a computational approach to show that FSCs have to form via local rather than global plasticity and be moderately large to impact sVm.
format article
author Balázs B. Ujfalussy
Judit K. Makara
author_facet Balázs B. Ujfalussy
Judit K. Makara
author_sort Balázs B. Ujfalussy
title Impact of functional synapse clusters on neuronal response selectivity
title_short Impact of functional synapse clusters on neuronal response selectivity
title_full Impact of functional synapse clusters on neuronal response selectivity
title_fullStr Impact of functional synapse clusters on neuronal response selectivity
title_full_unstemmed Impact of functional synapse clusters on neuronal response selectivity
title_sort impact of functional synapse clusters on neuronal response selectivity
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/26deb0c6b32c4646ba6e041777e4dbff
work_keys_str_mv AT balazsbujfalussy impactoffunctionalsynapseclustersonneuronalresponseselectivity
AT juditkmakara impactoffunctionalsynapseclustersonneuronalresponseselectivity
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