First report on molecular docking analysis and drug resistance substitutions to approved HCV NS5A and NS5B inhibitors amongst Iranian patients

First report on molecular docking analysis and drug resistance substitutions to approved HCV NS5A and NS5B inhibitors amongst Iranian patients

Abstract Background NS5A and NS5B proteins of hepatitis C virus (HCV) are the main targets of compounds that directly inhibit HCV infections. However, the emergence of resistance-associated substitutions (RASs) may cause substantial reductions in susceptibility to inhibitors. Methods Viral load and...

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Detalles Bibliográficos
Autores principales: Zahra Hasanshahi, Ava Hashempour, Farzane Ghasabi, Javad Moayedi, Zahra Musavi, Behzad Dehghani, Heidar Sharafi, Hassan Joulaei
Formato: article
Lenguaje:EN
Publicado: BMC 2021
Materias:
HCV
NS5A
NS5B
Drug-resistance
Bioinformatics
Iran
Diseases of the digestive system. Gastroenterology
RC799-869
Acceso en línea:https://doaj.org/article/26e1999e836e4135ad9b6588156afa79
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