The role of gut microbiota in metabolic regulation

Obesity and metabolic syndrome are among the major problems of modern society. The increase in obesity is associated with a corresponding increase in type 2 diabetes, cardiovascular disease and cancer. A huge amount of scientific research has been devoted to the development of methods to reduce obes...

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Autores principales: Ekaterina N. Kravchuk, Alexander E. Neimark, Elena N. Grineva, Mikhail M. Galagudza
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Lenguaje:EN
RU
Publicado: Endocrinology Research Centre 2016
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Acceso en línea:https://doaj.org/article/26e22d75208842fc9a8b25a64da707e1
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spelling oai:doaj.org-article:26e22d75208842fc9a8b25a64da707e12021-11-14T09:00:20ZThe role of gut microbiota in metabolic regulation2072-03512072-037810.14341/DM7704https://doaj.org/article/26e22d75208842fc9a8b25a64da707e12016-11-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/7704https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Obesity and metabolic syndrome are among the major problems of modern society. The increase in obesity is associated with a corresponding increase in type 2 diabetes, cardiovascular disease and cancer. A huge amount of scientific research has been devoted to the development of methods to reduce obesity and its complications. In recent years, attention has shifted towards studying the intestinal microbiota not only as a possible component of the pathological process but also as a target of therapeutic intervention. Recent evidence, primarily from investigations in animal models, suggests that the intestinal microbiota affects nutrient acquisition and energy regulation. This review will discuss the role of the intestinal microbiota in metabolic processes as well as the latest developments on the improvement of disturbances specific to obesity and metabolic syndrome.Ekaterina N. KravchukAlexander E. NeimarkElena N. GrinevaMikhail M. GalagudzaEndocrinology Research Centrearticleintestinal microbiotaobesitymetabolic syndromeshort-chain fatty acidbile acidNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 19, Iss 4, Pp 280-285 (2016)
institution DOAJ
collection DOAJ
language EN
RU
topic intestinal microbiota
obesity
metabolic syndrome
short-chain fatty acid
bile acid
Nutritional diseases. Deficiency diseases
RC620-627
spellingShingle intestinal microbiota
obesity
metabolic syndrome
short-chain fatty acid
bile acid
Nutritional diseases. Deficiency diseases
RC620-627
Ekaterina N. Kravchuk
Alexander E. Neimark
Elena N. Grineva
Mikhail M. Galagudza
The role of gut microbiota in metabolic regulation
description Obesity and metabolic syndrome are among the major problems of modern society. The increase in obesity is associated with a corresponding increase in type 2 diabetes, cardiovascular disease and cancer. A huge amount of scientific research has been devoted to the development of methods to reduce obesity and its complications. In recent years, attention has shifted towards studying the intestinal microbiota not only as a possible component of the pathological process but also as a target of therapeutic intervention. Recent evidence, primarily from investigations in animal models, suggests that the intestinal microbiota affects nutrient acquisition and energy regulation. This review will discuss the role of the intestinal microbiota in metabolic processes as well as the latest developments on the improvement of disturbances specific to obesity and metabolic syndrome.
format article
author Ekaterina N. Kravchuk
Alexander E. Neimark
Elena N. Grineva
Mikhail M. Galagudza
author_facet Ekaterina N. Kravchuk
Alexander E. Neimark
Elena N. Grineva
Mikhail M. Galagudza
author_sort Ekaterina N. Kravchuk
title The role of gut microbiota in metabolic regulation
title_short The role of gut microbiota in metabolic regulation
title_full The role of gut microbiota in metabolic regulation
title_fullStr The role of gut microbiota in metabolic regulation
title_full_unstemmed The role of gut microbiota in metabolic regulation
title_sort role of gut microbiota in metabolic regulation
publisher Endocrinology Research Centre
publishDate 2016
url https://doaj.org/article/26e22d75208842fc9a8b25a64da707e1
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