The role of gut microbiota in metabolic regulation
Obesity and metabolic syndrome are among the major problems of modern society. The increase in obesity is associated with a corresponding increase in type 2 diabetes, cardiovascular disease and cancer. A huge amount of scientific research has been devoted to the development of methods to reduce obes...
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Endocrinology Research Centre
2016
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oai:doaj.org-article:26e22d75208842fc9a8b25a64da707e12021-11-14T09:00:20ZThe role of gut microbiota in metabolic regulation2072-03512072-037810.14341/DM7704https://doaj.org/article/26e22d75208842fc9a8b25a64da707e12016-11-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/7704https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Obesity and metabolic syndrome are among the major problems of modern society. The increase in obesity is associated with a corresponding increase in type 2 diabetes, cardiovascular disease and cancer. A huge amount of scientific research has been devoted to the development of methods to reduce obesity and its complications. In recent years, attention has shifted towards studying the intestinal microbiota not only as a possible component of the pathological process but also as a target of therapeutic intervention. Recent evidence, primarily from investigations in animal models, suggests that the intestinal microbiota affects nutrient acquisition and energy regulation. This review will discuss the role of the intestinal microbiota in metabolic processes as well as the latest developments on the improvement of disturbances specific to obesity and metabolic syndrome.Ekaterina N. KravchukAlexander E. NeimarkElena N. GrinevaMikhail M. GalagudzaEndocrinology Research Centrearticleintestinal microbiotaobesitymetabolic syndromeshort-chain fatty acidbile acidNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 19, Iss 4, Pp 280-285 (2016) |
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DOAJ |
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EN RU |
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intestinal microbiota obesity metabolic syndrome short-chain fatty acid bile acid Nutritional diseases. Deficiency diseases RC620-627 |
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intestinal microbiota obesity metabolic syndrome short-chain fatty acid bile acid Nutritional diseases. Deficiency diseases RC620-627 Ekaterina N. Kravchuk Alexander E. Neimark Elena N. Grineva Mikhail M. Galagudza The role of gut microbiota in metabolic regulation |
description |
Obesity and metabolic syndrome are among the major problems of modern society. The increase in obesity is associated with a corresponding increase in type 2 diabetes, cardiovascular disease and cancer. A huge amount of scientific research has been devoted to the development of methods to reduce obesity and its complications. In recent years, attention has shifted towards studying the intestinal microbiota not only as a possible component of the pathological process but also as a target of therapeutic intervention. Recent evidence, primarily from investigations in animal models, suggests that the intestinal microbiota affects nutrient acquisition and energy regulation. This review will discuss the role of the intestinal microbiota in metabolic processes as well as the latest developments on the improvement of disturbances specific to obesity and metabolic syndrome. |
format |
article |
author |
Ekaterina N. Kravchuk Alexander E. Neimark Elena N. Grineva Mikhail M. Galagudza |
author_facet |
Ekaterina N. Kravchuk Alexander E. Neimark Elena N. Grineva Mikhail M. Galagudza |
author_sort |
Ekaterina N. Kravchuk |
title |
The role of gut microbiota in metabolic regulation |
title_short |
The role of gut microbiota in metabolic regulation |
title_full |
The role of gut microbiota in metabolic regulation |
title_fullStr |
The role of gut microbiota in metabolic regulation |
title_full_unstemmed |
The role of gut microbiota in metabolic regulation |
title_sort |
role of gut microbiota in metabolic regulation |
publisher |
Endocrinology Research Centre |
publishDate |
2016 |
url |
https://doaj.org/article/26e22d75208842fc9a8b25a64da707e1 |
work_keys_str_mv |
AT ekaterinankravchuk theroleofgutmicrobiotainmetabolicregulation AT alexandereneimark theroleofgutmicrobiotainmetabolicregulation AT elenangrineva theroleofgutmicrobiotainmetabolicregulation AT mikhailmgalagudza theroleofgutmicrobiotainmetabolicregulation AT ekaterinankravchuk roleofgutmicrobiotainmetabolicregulation AT alexandereneimark roleofgutmicrobiotainmetabolicregulation AT elenangrineva roleofgutmicrobiotainmetabolicregulation AT mikhailmgalagudza roleofgutmicrobiotainmetabolicregulation |
_version_ |
1718429514303799296 |