Optogenetic protein clustering through fluorescent protein tagging and extension of CRY2

Cryptochrome 2 (CRY2) from A. thaliana can be used to control light-dependent protein homo-oligomerization, but the molecular mechanism of CRY2 clustering is not known, limiting its application. Here the authors identify determinants of CRY2 clustering and engineer fusion partners to modulate cluste...

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Autores principales: Hyerim Park, Na Yeon Kim, Sangkyu Lee, Nury Kim, Jihoon Kim, Won Do Heo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/26ec3d5eb3ea4af4bf639ba1a8b42b5d
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spelling oai:doaj.org-article:26ec3d5eb3ea4af4bf639ba1a8b42b5d2021-12-02T10:48:28ZOptogenetic protein clustering through fluorescent protein tagging and extension of CRY210.1038/s41467-017-00060-22041-1723https://doaj.org/article/26ec3d5eb3ea4af4bf639ba1a8b42b5d2017-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00060-2https://doaj.org/toc/2041-1723Cryptochrome 2 (CRY2) from A. thaliana can be used to control light-dependent protein homo-oligomerization, but the molecular mechanism of CRY2 clustering is not known, limiting its application. Here the authors identify determinants of CRY2 clustering and engineer fusion partners to modulate clustering efficiency.Hyerim ParkNa Yeon KimSangkyu LeeNury KimJihoon KimWon Do HeoNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Hyerim Park
Na Yeon Kim
Sangkyu Lee
Nury Kim
Jihoon Kim
Won Do Heo
Optogenetic protein clustering through fluorescent protein tagging and extension of CRY2
description Cryptochrome 2 (CRY2) from A. thaliana can be used to control light-dependent protein homo-oligomerization, but the molecular mechanism of CRY2 clustering is not known, limiting its application. Here the authors identify determinants of CRY2 clustering and engineer fusion partners to modulate clustering efficiency.
format article
author Hyerim Park
Na Yeon Kim
Sangkyu Lee
Nury Kim
Jihoon Kim
Won Do Heo
author_facet Hyerim Park
Na Yeon Kim
Sangkyu Lee
Nury Kim
Jihoon Kim
Won Do Heo
author_sort Hyerim Park
title Optogenetic protein clustering through fluorescent protein tagging and extension of CRY2
title_short Optogenetic protein clustering through fluorescent protein tagging and extension of CRY2
title_full Optogenetic protein clustering through fluorescent protein tagging and extension of CRY2
title_fullStr Optogenetic protein clustering through fluorescent protein tagging and extension of CRY2
title_full_unstemmed Optogenetic protein clustering through fluorescent protein tagging and extension of CRY2
title_sort optogenetic protein clustering through fluorescent protein tagging and extension of cry2
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/26ec3d5eb3ea4af4bf639ba1a8b42b5d
work_keys_str_mv AT hyerimpark optogeneticproteinclusteringthroughfluorescentproteintaggingandextensionofcry2
AT nayeonkim optogeneticproteinclusteringthroughfluorescentproteintaggingandextensionofcry2
AT sangkyulee optogeneticproteinclusteringthroughfluorescentproteintaggingandextensionofcry2
AT nurykim optogeneticproteinclusteringthroughfluorescentproteintaggingandextensionofcry2
AT jihoonkim optogeneticproteinclusteringthroughfluorescentproteintaggingandextensionofcry2
AT wondoheo optogeneticproteinclusteringthroughfluorescentproteintaggingandextensionofcry2
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