Optogenetic protein clustering through fluorescent protein tagging and extension of CRY2
Cryptochrome 2 (CRY2) from A. thaliana can be used to control light-dependent protein homo-oligomerization, but the molecular mechanism of CRY2 clustering is not known, limiting its application. Here the authors identify determinants of CRY2 clustering and engineer fusion partners to modulate cluste...
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Nature Portfolio
2017
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oai:doaj.org-article:26ec3d5eb3ea4af4bf639ba1a8b42b5d2021-12-02T10:48:28ZOptogenetic protein clustering through fluorescent protein tagging and extension of CRY210.1038/s41467-017-00060-22041-1723https://doaj.org/article/26ec3d5eb3ea4af4bf639ba1a8b42b5d2017-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00060-2https://doaj.org/toc/2041-1723Cryptochrome 2 (CRY2) from A. thaliana can be used to control light-dependent protein homo-oligomerization, but the molecular mechanism of CRY2 clustering is not known, limiting its application. Here the authors identify determinants of CRY2 clustering and engineer fusion partners to modulate clustering efficiency.Hyerim ParkNa Yeon KimSangkyu LeeNury KimJihoon KimWon Do HeoNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-8 (2017) |
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Science Q Hyerim Park Na Yeon Kim Sangkyu Lee Nury Kim Jihoon Kim Won Do Heo Optogenetic protein clustering through fluorescent protein tagging and extension of CRY2 |
description |
Cryptochrome 2 (CRY2) from A. thaliana can be used to control light-dependent protein homo-oligomerization, but the molecular mechanism of CRY2 clustering is not known, limiting its application. Here the authors identify determinants of CRY2 clustering and engineer fusion partners to modulate clustering efficiency. |
format |
article |
author |
Hyerim Park Na Yeon Kim Sangkyu Lee Nury Kim Jihoon Kim Won Do Heo |
author_facet |
Hyerim Park Na Yeon Kim Sangkyu Lee Nury Kim Jihoon Kim Won Do Heo |
author_sort |
Hyerim Park |
title |
Optogenetic protein clustering through fluorescent protein tagging and extension of CRY2 |
title_short |
Optogenetic protein clustering through fluorescent protein tagging and extension of CRY2 |
title_full |
Optogenetic protein clustering through fluorescent protein tagging and extension of CRY2 |
title_fullStr |
Optogenetic protein clustering through fluorescent protein tagging and extension of CRY2 |
title_full_unstemmed |
Optogenetic protein clustering through fluorescent protein tagging and extension of CRY2 |
title_sort |
optogenetic protein clustering through fluorescent protein tagging and extension of cry2 |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/26ec3d5eb3ea4af4bf639ba1a8b42b5d |
work_keys_str_mv |
AT hyerimpark optogeneticproteinclusteringthroughfluorescentproteintaggingandextensionofcry2 AT nayeonkim optogeneticproteinclusteringthroughfluorescentproteintaggingandextensionofcry2 AT sangkyulee optogeneticproteinclusteringthroughfluorescentproteintaggingandextensionofcry2 AT nurykim optogeneticproteinclusteringthroughfluorescentproteintaggingandextensionofcry2 AT jihoonkim optogeneticproteinclusteringthroughfluorescentproteintaggingandextensionofcry2 AT wondoheo optogeneticproteinclusteringthroughfluorescentproteintaggingandextensionofcry2 |
_version_ |
1718396637105094656 |