Defining obesity cut-off points for migrant South Asians.

<h4>Background</h4>Body mass index (BMI) and waist circumference (WC) are used to define cardiovascular and type 2 diabetes risk. We aimed to derive appropriate BMI and WC obesity cut-off points in a migrant South Asian population.<h4>Methods</h4>4688 White Europeans and 1333...

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Autores principales:	Laura J Gray, Thomas Yates, Melanie J Davies, Emer Brady, David R Webb, Naveed Sattar, Kamlesh Khunti
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2011
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/26fdf43e9bae413fa60c3d144920784b
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spelling	oai:doaj.org-article:26fdf43e9bae413fa60c3d144920784b2021-11-18T07:36:06ZDefining obesity cut-off points for migrant South Asians.1932-620310.1371/journal.pone.0026464https://doaj.org/article/26fdf43e9bae413fa60c3d144920784b2011-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22039493/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>Body mass index (BMI) and waist circumference (WC) are used to define cardiovascular and type 2 diabetes risk. We aimed to derive appropriate BMI and WC obesity cut-off points in a migrant South Asian population.<h4>Methods</h4>4688 White Europeans and 1333 South Asians resident in the UK aged 40-75 years inclusive were screened for type 2 diabetes. Principal components analysis was used to derive a glycaemia, lipid, and a blood pressure factor. Regression models for each factor, adjusted for age and stratified by sex, were used to identify BMI and WC cut-off points in South Asians that correspond to those defined for White Europeans.<h4>Findings</h4>For South Asian males, derived BMI obesity cut-off points equivalent to 30.0 kg/m(2) in White Europeans were 22.6 kg/m(2) (95% Confidence Interval (95% CI) 20.7 kg/m(2) to 24.5 kg/m(2)) for the glycaemia factor, 26.0 kg/m(2) (95% CI 24.7 kg/m(2) to 27.3 kg/m(2)) for the lipid factor, and 28.4 kg/m(2) (95% CI 26.5 kg/m(2) to 30.4 kg/m(2)) for the blood pressure factor. For WC, derived cut-off points for South Asian males equivalent to 102 cm in White Europeans were 83.8 cm (95% CI 79.3 cm to 88.2 cm) for the glycaemia factor, 91.4 cm (95% CI 86.9 cm to 95.8 cm) for the lipid factor, and 99.3 cm (95% CI 93.3 cm to 105.2 cm) for the blood pressure factor. Lower ethnicity cut-off points were seen for females for both BMI and WC.<h4>Conclusions</h4>Substantially lower obesity cut-off points are needed in South Asians to detect an equivalent level of dysglycemia and dyslipidemia as observed in White Europeans. South Asian ethnicity could be considered as a similar level of risk as obesity (in White Europeans) for the development of type 2 diabetes.Laura J GrayThomas YatesMelanie J DaviesEmer BradyDavid R WebbNaveed SattarKamlesh KhuntiPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 6, Iss 10, p e26464 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Laura J Gray Thomas Yates Melanie J Davies Emer Brady David R Webb Naveed Sattar Kamlesh Khunti Defining obesity cut-off points for migrant South Asians.
description	<h4>Background</h4>Body mass index (BMI) and waist circumference (WC) are used to define cardiovascular and type 2 diabetes risk. We aimed to derive appropriate BMI and WC obesity cut-off points in a migrant South Asian population.<h4>Methods</h4>4688 White Europeans and 1333 South Asians resident in the UK aged 40-75 years inclusive were screened for type 2 diabetes. Principal components analysis was used to derive a glycaemia, lipid, and a blood pressure factor. Regression models for each factor, adjusted for age and stratified by sex, were used to identify BMI and WC cut-off points in South Asians that correspond to those defined for White Europeans.<h4>Findings</h4>For South Asian males, derived BMI obesity cut-off points equivalent to 30.0 kg/m(2) in White Europeans were 22.6 kg/m(2) (95% Confidence Interval (95% CI) 20.7 kg/m(2) to 24.5 kg/m(2)) for the glycaemia factor, 26.0 kg/m(2) (95% CI 24.7 kg/m(2) to 27.3 kg/m(2)) for the lipid factor, and 28.4 kg/m(2) (95% CI 26.5 kg/m(2) to 30.4 kg/m(2)) for the blood pressure factor. For WC, derived cut-off points for South Asian males equivalent to 102 cm in White Europeans were 83.8 cm (95% CI 79.3 cm to 88.2 cm) for the glycaemia factor, 91.4 cm (95% CI 86.9 cm to 95.8 cm) for the lipid factor, and 99.3 cm (95% CI 93.3 cm to 105.2 cm) for the blood pressure factor. Lower ethnicity cut-off points were seen for females for both BMI and WC.<h4>Conclusions</h4>Substantially lower obesity cut-off points are needed in South Asians to detect an equivalent level of dysglycemia and dyslipidemia as observed in White Europeans. South Asian ethnicity could be considered as a similar level of risk as obesity (in White Europeans) for the development of type 2 diabetes.
format	article
author	Laura J Gray Thomas Yates Melanie J Davies Emer Brady David R Webb Naveed Sattar Kamlesh Khunti
author_facet	Laura J Gray Thomas Yates Melanie J Davies Emer Brady David R Webb Naveed Sattar Kamlesh Khunti
author_sort	Laura J Gray
title	Defining obesity cut-off points for migrant South Asians.
title_short	Defining obesity cut-off points for migrant South Asians.
title_full	Defining obesity cut-off points for migrant South Asians.
title_fullStr	Defining obesity cut-off points for migrant South Asians.
title_full_unstemmed	Defining obesity cut-off points for migrant South Asians.
title_sort	defining obesity cut-off points for migrant south asians.
publisher	Public Library of Science (PLoS)
publishDate	2011
url	https://doaj.org/article/26fdf43e9bae413fa60c3d144920784b
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Defining obesity cut-off points for migrant South Asians.

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