Synergistic lipid compositions for albumin receptor mediated delivery of mRNA to the liver

Lipid-like nanoparticles have applications as non-viral delivery systems for mRNA. Here, the authors develop biodegradable lipids with improved clearance and reduced toxicity.

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Detalles Bibliográficos
Autores principales: Lei Miao, Jiaqi Lin, Yuxuan Huang, Linxian Li, Derfogail Delcassian, Yifan Ge, Yunhua Shi, Daniel G. Anderson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/27030fbe450d4d599833b622ebae74de
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