Information recovery from low coverage whole-genome bisulfite sequencing

Here, Libertini and colleagues devise a computation tool that can analyze whole-genome bisulfite sequencing (WGBS) data to recover of ∼30% of the lost differential methylation position information. They use COMETgazer and COMETvintage to analyze 13 diffferent methylome data to demonstrate their perf...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Emanuele Libertini, Simon C. Heath, Rifat A. Hamoudi, Marta Gut, Michael J. Ziller, Agata Czyz, Victor Ruotti, Hendrik G. Stunnenberg, Mattia Frontini, Willem H. Ouwehand, Alexander Meissner, Ivo G. Gut, Stephan Beck
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/270685d69411490d83bf90eb1cdafc89
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:270685d69411490d83bf90eb1cdafc89
record_format	dspace
spelling	oai:doaj.org-article:270685d69411490d83bf90eb1cdafc892021-12-02T17:31:17ZInformation recovery from low coverage whole-genome bisulfite sequencing10.1038/ncomms113062041-1723https://doaj.org/article/270685d69411490d83bf90eb1cdafc892016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11306https://doaj.org/toc/2041-1723Here, Libertini and colleagues devise a computation tool that can analyze whole-genome bisulfite sequencing (WGBS) data to recover of ∼30% of the lost differential methylation position information. They use COMETgazer and COMETvintage to analyze 13 diffferent methylome data to demonstrate their performance.Emanuele LibertiniSimon C. HeathRifat A. HamoudiMarta GutMichael J. ZillerAgata CzyzVictor RuottiHendrik G. StunnenbergMattia FrontiniWillem H. OuwehandAlexander MeissnerIvo G. GutStephan BeckNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Emanuele Libertini Simon C. Heath Rifat A. Hamoudi Marta Gut Michael J. Ziller Agata Czyz Victor Ruotti Hendrik G. Stunnenberg Mattia Frontini Willem H. Ouwehand Alexander Meissner Ivo G. Gut Stephan Beck Information recovery from low coverage whole-genome bisulfite sequencing
description	Here, Libertini and colleagues devise a computation tool that can analyze whole-genome bisulfite sequencing (WGBS) data to recover of ∼30% of the lost differential methylation position information. They use COMETgazer and COMETvintage to analyze 13 diffferent methylome data to demonstrate their performance.
format	article
author	Emanuele Libertini Simon C. Heath Rifat A. Hamoudi Marta Gut Michael J. Ziller Agata Czyz Victor Ruotti Hendrik G. Stunnenberg Mattia Frontini Willem H. Ouwehand Alexander Meissner Ivo G. Gut Stephan Beck
author_facet	Emanuele Libertini Simon C. Heath Rifat A. Hamoudi Marta Gut Michael J. Ziller Agata Czyz Victor Ruotti Hendrik G. Stunnenberg Mattia Frontini Willem H. Ouwehand Alexander Meissner Ivo G. Gut Stephan Beck
author_sort	Emanuele Libertini
title	Information recovery from low coverage whole-genome bisulfite sequencing
title_short	Information recovery from low coverage whole-genome bisulfite sequencing
title_full	Information recovery from low coverage whole-genome bisulfite sequencing
title_fullStr	Information recovery from low coverage whole-genome bisulfite sequencing
title_full_unstemmed	Information recovery from low coverage whole-genome bisulfite sequencing
title_sort	information recovery from low coverage whole-genome bisulfite sequencing
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/270685d69411490d83bf90eb1cdafc89
work_keys_str_mv	AT emanuelelibertini informationrecoveryfromlowcoveragewholegenomebisulfitesequencing AT simoncheath informationrecoveryfromlowcoveragewholegenomebisulfitesequencing AT rifatahamoudi informationrecoveryfromlowcoveragewholegenomebisulfitesequencing AT martagut informationrecoveryfromlowcoveragewholegenomebisulfitesequencing AT michaeljziller informationrecoveryfromlowcoveragewholegenomebisulfitesequencing AT agataczyz informationrecoveryfromlowcoveragewholegenomebisulfitesequencing AT victorruotti informationrecoveryfromlowcoveragewholegenomebisulfitesequencing AT hendrikgstunnenberg informationrecoveryfromlowcoveragewholegenomebisulfitesequencing AT mattiafrontini informationrecoveryfromlowcoveragewholegenomebisulfitesequencing AT willemhouwehand informationrecoveryfromlowcoveragewholegenomebisulfitesequencing AT alexandermeissner informationrecoveryfromlowcoveragewholegenomebisulfitesequencing AT ivoggut informationrecoveryfromlowcoveragewholegenomebisulfitesequencing AT stephanbeck informationrecoveryfromlowcoveragewholegenomebisulfitesequencing
_version_	1718380661379694592

Information recovery from low coverage whole-genome bisulfite sequencing

Ejemplares similares