TDP-43 is not a common cause of sporadic amyotrophic lateral sclerosis.
<h4>Background</h4>TAR DNA binding protein, encoded by TARDBP, was shown to be a central component of ubiquitin-positive, tau-negative inclusions in frontotemporal lobar degeneration (FTLD-U) and amyotrophic lateral sclerosis (ALS). Recently, mutations in TARDBP have been linked to famil...
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| Auteurs principaux: | , , , , , |
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| Format: | article |
| Langue: | EN |
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Public Library of Science (PLoS)
2008
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| Accès en ligne: | https://doaj.org/article/27099a73191a4f369aeb28c169b83464 |
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