TDP-43 is not a common cause of sporadic amyotrophic lateral sclerosis.

TDP-43 is not a common cause of sporadic amyotrophic lateral sclerosis.

<h4>Background</h4>TAR DNA binding protein, encoded by TARDBP, was shown to be a central component of ubiquitin-positive, tau-negative inclusions in frontotemporal lobar degeneration (FTLD-U) and amyotrophic lateral sclerosis (ALS). Recently, mutations in TARDBP have been linked to famil...

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Autores principales: Rita J Guerreiro, Jennifer C Schymick, Cynthia Crews, Andrew Singleton, John Hardy, Bryan J Traynor
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2008
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/27099a73191a4f369aeb28c169b83464
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