Single-molecule sensing of peptides and nucleic acids by engineered aerolysin nanopores

Aerolysin pores have potential to improve the accuracy of DNA sequencing and single-molecule proteomics. Here, the authors rationally design a set of mutated pores to achieve a more accurate detection of peptides and nucleic acids.

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Autores principales:	Chan Cao, Nuria Cirauqui, Maria Jose Marcaida, Elena Buglakova, Alice Duperrex, Aleksandra Radenovic, Matteo Dal Peraro
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/27165b7a4d1542c79d4bf6e6931d454d
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spelling	oai:doaj.org-article:27165b7a4d1542c79d4bf6e6931d454d2021-12-02T14:38:59ZSingle-molecule sensing of peptides and nucleic acids by engineered aerolysin nanopores10.1038/s41467-019-12690-92041-1723https://doaj.org/article/27165b7a4d1542c79d4bf6e6931d454d2019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12690-9https://doaj.org/toc/2041-1723Aerolysin pores have potential to improve the accuracy of DNA sequencing and single-molecule proteomics. Here, the authors rationally design a set of mutated pores to achieve a more accurate detection of peptides and nucleic acids.Chan CaoNuria CirauquiMaria Jose MarcaidaElena BuglakovaAlice DuperrexAleksandra RadenovicMatteo Dal PeraroNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chan Cao Nuria Cirauqui Maria Jose Marcaida Elena Buglakova Alice Duperrex Aleksandra Radenovic Matteo Dal Peraro Single-molecule sensing of peptides and nucleic acids by engineered aerolysin nanopores
description	Aerolysin pores have potential to improve the accuracy of DNA sequencing and single-molecule proteomics. Here, the authors rationally design a set of mutated pores to achieve a more accurate detection of peptides and nucleic acids.
format	article
author	Chan Cao Nuria Cirauqui Maria Jose Marcaida Elena Buglakova Alice Duperrex Aleksandra Radenovic Matteo Dal Peraro
author_facet	Chan Cao Nuria Cirauqui Maria Jose Marcaida Elena Buglakova Alice Duperrex Aleksandra Radenovic Matteo Dal Peraro
author_sort	Chan Cao
title	Single-molecule sensing of peptides and nucleic acids by engineered aerolysin nanopores
title_short	Single-molecule sensing of peptides and nucleic acids by engineered aerolysin nanopores
title_full	Single-molecule sensing of peptides and nucleic acids by engineered aerolysin nanopores
title_fullStr	Single-molecule sensing of peptides and nucleic acids by engineered aerolysin nanopores
title_full_unstemmed	Single-molecule sensing of peptides and nucleic acids by engineered aerolysin nanopores
title_sort	single-molecule sensing of peptides and nucleic acids by engineered aerolysin nanopores
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/27165b7a4d1542c79d4bf6e6931d454d
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Single-molecule sensing of peptides and nucleic acids by engineered aerolysin nanopores

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