Single-molecule sensing of peptides and nucleic acids by engineered aerolysin nanopores
Aerolysin pores have potential to improve the accuracy of DNA sequencing and single-molecule proteomics. Here, the authors rationally design a set of mutated pores to achieve a more accurate detection of peptides and nucleic acids.
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Auteurs principaux: | Chan Cao, Nuria Cirauqui, Maria Jose Marcaida, Elena Buglakova, Alice Duperrex, Aleksandra Radenovic, Matteo Dal Peraro |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2019
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Accès en ligne: | https://doaj.org/article/27165b7a4d1542c79d4bf6e6931d454d |
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