Single-molecule sensing of peptides and nucleic acids by engineered aerolysin nanopores
Aerolysin pores have potential to improve the accuracy of DNA sequencing and single-molecule proteomics. Here, the authors rationally design a set of mutated pores to achieve a more accurate detection of peptides and nucleic acids.
Guardado en:
Autores principales: | Chan Cao, Nuria Cirauqui, Maria Jose Marcaida, Elena Buglakova, Alice Duperrex, Aleksandra Radenovic, Matteo Dal Peraro |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/27165b7a4d1542c79d4bf6e6931d454d |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Mapping the sensing spots of aerolysin for single oligonucleotides analysis
por: Chan Cao, et al.
Publicado: (2018) -
Cryo-EM structure of aerolysin variants reveals a novel protein fold and the pore-formation process
por: Ioan Iacovache, et al.
Publicado: (2016) -
Identification of single amino acid differences in uniformly charged homopolymeric peptides with aerolysin nanopore
por: Fabien Piguet, et al.
Publicado: (2018) -
Dual chaperone role of the C-terminal propeptide in folding and oligomerization of the pore-forming toxin aerolysin.
por: Ioan Iacovache, et al.
Publicado: (2011) -
Nanopore sensing at ultra-low concentrations using single-molecule dielectrophoretic trapping
por: Kevin J. Freedman, et al.
Publicado: (2016)