Neurohormonal signaling via a sulfotransferase antagonizes insulin-like signaling to regulate a Caenorhabditis elegans stress response

Reduced insulin-like signaling is required for C. elegans response to many environmental stressors, but how distinct outcomes are achieved is unknown. The authors show that the cytosolic sulfotransferase SSU-1 controls neurohormonal signaling via NHR-1 to specify the animals’ osmotic stress response...

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Autores principales:	Nicholas O. Burton, Vivek K. Dwivedi, Kirk B. Burkhart, Rebecca E. W. Kaplan, L. Ryan Baugh, H. Robert Horvitz
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/271b5981c06947da9c73c1694ff3a2a9
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spelling	oai:doaj.org-article:271b5981c06947da9c73c1694ff3a2a92021-12-02T15:33:58ZNeurohormonal signaling via a sulfotransferase antagonizes insulin-like signaling to regulate a Caenorhabditis elegans stress response10.1038/s41467-018-07640-w2041-1723https://doaj.org/article/271b5981c06947da9c73c1694ff3a2a92018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07640-whttps://doaj.org/toc/2041-1723Reduced insulin-like signaling is required for C. elegans response to many environmental stressors, but how distinct outcomes are achieved is unknown. The authors show that the cytosolic sulfotransferase SSU-1 controls neurohormonal signaling via NHR-1 to specify the animals’ osmotic stress response.Nicholas O. BurtonVivek K. DwivediKirk B. BurkhartRebecca E. W. KaplanL. Ryan BaughH. Robert HorvitzNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nicholas O. Burton Vivek K. Dwivedi Kirk B. Burkhart Rebecca E. W. Kaplan L. Ryan Baugh H. Robert Horvitz Neurohormonal signaling via a sulfotransferase antagonizes insulin-like signaling to regulate a Caenorhabditis elegans stress response
description	Reduced insulin-like signaling is required for C. elegans response to many environmental stressors, but how distinct outcomes are achieved is unknown. The authors show that the cytosolic sulfotransferase SSU-1 controls neurohormonal signaling via NHR-1 to specify the animals’ osmotic stress response.
format	article
author	Nicholas O. Burton Vivek K. Dwivedi Kirk B. Burkhart Rebecca E. W. Kaplan L. Ryan Baugh H. Robert Horvitz
author_facet	Nicholas O. Burton Vivek K. Dwivedi Kirk B. Burkhart Rebecca E. W. Kaplan L. Ryan Baugh H. Robert Horvitz
author_sort	Nicholas O. Burton
title	Neurohormonal signaling via a sulfotransferase antagonizes insulin-like signaling to regulate a Caenorhabditis elegans stress response
title_short	Neurohormonal signaling via a sulfotransferase antagonizes insulin-like signaling to regulate a Caenorhabditis elegans stress response
title_full	Neurohormonal signaling via a sulfotransferase antagonizes insulin-like signaling to regulate a Caenorhabditis elegans stress response
title_fullStr	Neurohormonal signaling via a sulfotransferase antagonizes insulin-like signaling to regulate a Caenorhabditis elegans stress response
title_full_unstemmed	Neurohormonal signaling via a sulfotransferase antagonizes insulin-like signaling to regulate a Caenorhabditis elegans stress response
title_sort	neurohormonal signaling via a sulfotransferase antagonizes insulin-like signaling to regulate a caenorhabditis elegans stress response
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/271b5981c06947da9c73c1694ff3a2a9
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Neurohormonal signaling via a sulfotransferase antagonizes insulin-like signaling to regulate a Caenorhabditis elegans stress response

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