Current status of healthcare-associated enteroviral (non-polio) infections

Here we present the data on foreign research publications describing healthcare-associated enteroviral (nonpolio) infections (HAI) sought in the Worldwide Database for Nosocomial Outbreaks (Institut für Hygiene und Umweltmedizin, Universitȁtmedizincomplex “Charite”, Germany) as well as PubMed search...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	A. V. Alimov, E. P. Igonina, I. V. Feldblyum, V. I. Chalapa, Yu. A. Zakharova
Formato:	article
Lenguaje:	RU
Publicado:	Sankt-Peterburg : NIIÈM imeni Pastera 2020
Materias:	enteroviral (non-polio) infections nosocomial infections epidemic focus enteroviruses echovirus coxsackievirus Infectious and parasitic diseases RC109-216
Acceso en línea:	https://doaj.org/article/272c047a9a6c45039b6857cb545b5d9d
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:272c047a9a6c45039b6857cb545b5d9d
record_format	dspace
spelling	oai:doaj.org-article:272c047a9a6c45039b6857cb545b5d9d2021-11-22T07:09:54ZCurrent status of healthcare-associated enteroviral (non-polio) infections2220-76192313-739810.15789/10.15789/2220-7619-CSF-1161https://doaj.org/article/272c047a9a6c45039b6857cb545b5d9d2020-08-01T00:00:00Zhttps://www.iimmun.ru/iimm/article/view/1161https://doaj.org/toc/2220-7619https://doaj.org/toc/2313-7398Here we present the data on foreign research publications describing healthcare-associated enteroviral (nonpolio) infections (HAI) sought in the Worldwide Database for Nosocomial Outbreaks (Institut für Hygiene und Umweltmedizin, Universitȁtmedizincomplex “Charite”, Germany) as well as PubMed search engine (The United States National Library), covering 1936–2017 timeframe. The publications retrieved contained the data on 28 nosocomial outbreaks caused by Enterovirus A (EV-A71), В (Echoviruses 11, 17, 18, 30, 31, 33, Coxsackie viruses А9, В2, В5) and D (EV-D68). It was discovered that the majority of the nosocomial enteroviral (non-polio) outbreaks occurred in obstetric hospitals and neonatal units so that children were mainly maternally infected. In addition, a case associated with intrauterine infection was described. It was shown that outbreaks might be started by an infected child at the incubation period. Single publications reported nosocomial outbreaks in geriatric hospitals. Generally, nosocomial enteroviral (non-polio) outbreaks were characterized by polymorphic clinical picture caused by any certain pathogen serotype and within a single site of the infection. Few lethal outcomes were recorded. Enterovirus B species dominated among identified etiological agents. Violated hospital hygiene and infection control contributing to spread of infection were among those found in neonatal units: putting used diapers out on baby bed prior disposal, sharing bathtub, toys and household objects as well as poor hand hygiene in medical workers. One of the measures recommended to improve diagnostics of enteroviral (non-polio) infections was virology screening of children with suspected sepsis in case of unidentified etiology. It was established that etiological decoding of nosocomial outbreaks was impossible without applying pathogen-specific diagnostic tools, mainly nested RT-PCR and direct sequencing of followed by subsequent phylogenetic analysis.A. V. AlimovE. P. IgoninaI. V. FeldblyumV. I. ChalapaYu. A. ZakharovaSankt-Peterburg : NIIÈM imeni Pasteraarticleenteroviral (non-polio) infectionsnosocomial infectionsepidemic focusenterovirusesechoviruscoxsackievirusInfectious and parasitic diseasesRC109-216RUInfekciâ i Immunitet, Vol 10, Iss 3, Pp 486-496 (2020)
institution	DOAJ
collection	DOAJ
language	RU
topic	enteroviral (non-polio) infections nosocomial infections epidemic focus enteroviruses echovirus coxsackievirus Infectious and parasitic diseases RC109-216
spellingShingle	enteroviral (non-polio) infections nosocomial infections epidemic focus enteroviruses echovirus coxsackievirus Infectious and parasitic diseases RC109-216 A. V. Alimov E. P. Igonina I. V. Feldblyum V. I. Chalapa Yu. A. Zakharova Current status of healthcare-associated enteroviral (non-polio) infections
description	Here we present the data on foreign research publications describing healthcare-associated enteroviral (nonpolio) infections (HAI) sought in the Worldwide Database for Nosocomial Outbreaks (Institut für Hygiene und Umweltmedizin, Universitȁtmedizincomplex “Charite”, Germany) as well as PubMed search engine (The United States National Library), covering 1936–2017 timeframe. The publications retrieved contained the data on 28 nosocomial outbreaks caused by Enterovirus A (EV-A71), В (Echoviruses 11, 17, 18, 30, 31, 33, Coxsackie viruses А9, В2, В5) and D (EV-D68). It was discovered that the majority of the nosocomial enteroviral (non-polio) outbreaks occurred in obstetric hospitals and neonatal units so that children were mainly maternally infected. In addition, a case associated with intrauterine infection was described. It was shown that outbreaks might be started by an infected child at the incubation period. Single publications reported nosocomial outbreaks in geriatric hospitals. Generally, nosocomial enteroviral (non-polio) outbreaks were characterized by polymorphic clinical picture caused by any certain pathogen serotype and within a single site of the infection. Few lethal outcomes were recorded. Enterovirus B species dominated among identified etiological agents. Violated hospital hygiene and infection control contributing to spread of infection were among those found in neonatal units: putting used diapers out on baby bed prior disposal, sharing bathtub, toys and household objects as well as poor hand hygiene in medical workers. One of the measures recommended to improve diagnostics of enteroviral (non-polio) infections was virology screening of children with suspected sepsis in case of unidentified etiology. It was established that etiological decoding of nosocomial outbreaks was impossible without applying pathogen-specific diagnostic tools, mainly nested RT-PCR and direct sequencing of followed by subsequent phylogenetic analysis.
format	article
author	A. V. Alimov E. P. Igonina I. V. Feldblyum V. I. Chalapa Yu. A. Zakharova
author_facet	A. V. Alimov E. P. Igonina I. V. Feldblyum V. I. Chalapa Yu. A. Zakharova
author_sort	A. V. Alimov
title	Current status of healthcare-associated enteroviral (non-polio) infections
title_short	Current status of healthcare-associated enteroviral (non-polio) infections
title_full	Current status of healthcare-associated enteroviral (non-polio) infections
title_fullStr	Current status of healthcare-associated enteroviral (non-polio) infections
title_full_unstemmed	Current status of healthcare-associated enteroviral (non-polio) infections
title_sort	current status of healthcare-associated enteroviral (non-polio) infections
publisher	Sankt-Peterburg : NIIÈM imeni Pastera
publishDate	2020
url	https://doaj.org/article/272c047a9a6c45039b6857cb545b5d9d
work_keys_str_mv	AT avalimov currentstatusofhealthcareassociatedenteroviralnonpolioinfections AT epigonina currentstatusofhealthcareassociatedenteroviralnonpolioinfections AT ivfeldblyum currentstatusofhealthcareassociatedenteroviralnonpolioinfections AT vichalapa currentstatusofhealthcareassociatedenteroviralnonpolioinfections AT yuazakharova currentstatusofhealthcareassociatedenteroviralnonpolioinfections
_version_	1718417905937285120

Current status of healthcare-associated enteroviral (non-polio) infections

Ejemplares similares