Collagen XVII inhibits breast cancer cell proliferation and growth through deactivation of the AKT/mTOR signaling pathway.

Collagen XVII (COL17), a cell-matrix adhesion protein, has been found to be suppressed in breast cancer. Our previous data demonstrated a preventive role of COL17 in breast cancer invasiveness. The present study used the stable COL17-overexpressing MCF7 and MDA-MB-231 cells to reveal an anti-prolife...

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Auteurs principaux: Muttarin Lothong, Watchara Sakares, Pornchai Rojsitthisak, Chizu Tanikawa, Koichi Matsuda, Varalee Yodsurang
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2021
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R
Q
Accès en ligne:https://doaj.org/article/2731ce70639c48b587ebf373b27a6fd0
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