Bioactive toothpastes in dentin hypersensitivity treatment: A systematic review

Purpose: The use of bioactive materials is a recent proposal in the treatment of dentin hypersensitivity (DH) due to the ability to stimulate the neoformation of a barrier on dentin surface. Questions have arisen about the effectiveness of the materials to reduce DH when compared to the control grou...

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Autores principales:	Samantha Ariadne Alves de Freitas, Neurinéia Margarida Alves de Oliveira, Juliana Larocca de Geus, Soraia de Fátima Carvalho Souza, Adriana de Fátima Vasconcelos Pereira, José Bauer
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Dentin sensitivity Clinical trial Dentin desensitizing agents Bioactive glass Medicine R Dentistry RK1-715
Acceso en línea:	https://doaj.org/article/2735e9f3bdf24c6dbccf8d12192a4065
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spelling	oai:doaj.org-article:2735e9f3bdf24c6dbccf8d12192a40652021-11-10T04:20:42ZBioactive toothpastes in dentin hypersensitivity treatment: A systematic review1013-905210.1016/j.sdentj.2021.04.004https://doaj.org/article/2735e9f3bdf24c6dbccf8d12192a40652021-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S1013905221000481https://doaj.org/toc/1013-9052Purpose: The use of bioactive materials is a recent proposal in the treatment of dentin hypersensitivity (DH) due to the ability to stimulate the neoformation of a barrier on dentin surface. Questions have arisen about the effectiveness of the materials to reduce DH when compared to the control groups (placebo or non-bioactive substance). Thus, the aim of this systematic review was to evaluate the randomized controlled trials in adult patients for DH treatment with a dentifrice containing bioactive glass, applied either at-home or in-office. Methods: The study was registered in PROSPERO and followed PRISMA guidelines. Searches were carried out in four databases (Pubmed/Medline, CENTRAL, Wbb of Science, LILACS) spanning from February 2020 to March 2020, with no language or publication date restrictions. A supplementary hand-search was performed by checking the list of references. The so-called gray literature of the national and international databases for theses and dissertations, as well as unfinished, in progress and unpublished studies were also searched. Results: After reading the titles and abstracts, articles that were duplicated (74 records) or unrelated to the systematic review (76 records) were excluded. Fifteen studies were evaluated considering seven at low risk of bias, four at high risk and four at moderate risk. Conclusion: The bioactive compounds at low concentrations (2.5–7.5%) can be used as treatment of DH both at-home and in-office.Samantha Ariadne Alves de FreitasNeurinéia Margarida Alves de OliveiraJuliana Larocca de GeusSoraia de Fátima Carvalho SouzaAdriana de Fátima Vasconcelos PereiraJosé BauerElsevierarticleDentin sensitivityClinical trialDentin desensitizing agentsBioactive glassMedicineRDentistryRK1-715ENSaudi Dental Journal, Vol 33, Iss 7, Pp 395-403 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Dentin sensitivity Clinical trial Dentin desensitizing agents Bioactive glass Medicine R Dentistry RK1-715
spellingShingle	Dentin sensitivity Clinical trial Dentin desensitizing agents Bioactive glass Medicine R Dentistry RK1-715 Samantha Ariadne Alves de Freitas Neurinéia Margarida Alves de Oliveira Juliana Larocca de Geus Soraia de Fátima Carvalho Souza Adriana de Fátima Vasconcelos Pereira José Bauer Bioactive toothpastes in dentin hypersensitivity treatment: A systematic review
description	Purpose: The use of bioactive materials is a recent proposal in the treatment of dentin hypersensitivity (DH) due to the ability to stimulate the neoformation of a barrier on dentin surface. Questions have arisen about the effectiveness of the materials to reduce DH when compared to the control groups (placebo or non-bioactive substance). Thus, the aim of this systematic review was to evaluate the randomized controlled trials in adult patients for DH treatment with a dentifrice containing bioactive glass, applied either at-home or in-office. Methods: The study was registered in PROSPERO and followed PRISMA guidelines. Searches were carried out in four databases (Pubmed/Medline, CENTRAL, Wbb of Science, LILACS) spanning from February 2020 to March 2020, with no language or publication date restrictions. A supplementary hand-search was performed by checking the list of references. The so-called gray literature of the national and international databases for theses and dissertations, as well as unfinished, in progress and unpublished studies were also searched. Results: After reading the titles and abstracts, articles that were duplicated (74 records) or unrelated to the systematic review (76 records) were excluded. Fifteen studies were evaluated considering seven at low risk of bias, four at high risk and four at moderate risk. Conclusion: The bioactive compounds at low concentrations (2.5–7.5%) can be used as treatment of DH both at-home and in-office.
format	article
author	Samantha Ariadne Alves de Freitas Neurinéia Margarida Alves de Oliveira Juliana Larocca de Geus Soraia de Fátima Carvalho Souza Adriana de Fátima Vasconcelos Pereira José Bauer
author_facet	Samantha Ariadne Alves de Freitas Neurinéia Margarida Alves de Oliveira Juliana Larocca de Geus Soraia de Fátima Carvalho Souza Adriana de Fátima Vasconcelos Pereira José Bauer
author_sort	Samantha Ariadne Alves de Freitas
title	Bioactive toothpastes in dentin hypersensitivity treatment: A systematic review
title_short	Bioactive toothpastes in dentin hypersensitivity treatment: A systematic review
title_full	Bioactive toothpastes in dentin hypersensitivity treatment: A systematic review
title_fullStr	Bioactive toothpastes in dentin hypersensitivity treatment: A systematic review
title_full_unstemmed	Bioactive toothpastes in dentin hypersensitivity treatment: A systematic review
title_sort	bioactive toothpastes in dentin hypersensitivity treatment: a systematic review
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/2735e9f3bdf24c6dbccf8d12192a4065
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Bioactive toothpastes in dentin hypersensitivity treatment: A systematic review

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