Metabolomic characteristics of cholesterol-induced non-obese nonalcoholic fatty liver disease in mice

Metabolomic characteristics of cholesterol-induced non-obese nonalcoholic fatty liver disease in mice

Abstract Nonalcoholic fatty liver disease (NAFLD) in non-obese patients remains a clinical condition with unclear etiology and pathogenesis. Using a metabolomics approach in a mouse model that recapitulates almost all the characteristic features of non-obese NAFLD, we aimed to advance mechanistic un...

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Autores principales: Lan N. Tu, Megan R. Showalter, Tomas Cajka, Sili Fan, Viju V. Pillai, Oliver Fiehn, Vimal Selvaraj
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/273c2e5360d44f8d90ee63f1a2c4e581
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