The maternal to zygotic transition regulates genome-wide heterochromatin establishment in the zebrafish embryo

Eukaryotic genomes are segregated into euchromatin and heterochromatin. Here the authors show that heterochromatin establishment during zebrafish embryo development is controlled by zygotic transcription of miR-430 and subsequent degradation of maternal transcripts encoding the chromatin remodeling...

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Autores principales: Kathrin Laue, Srivarsha Rajshekar, Abigail J. Courtney, Zachary A. Lewis, Mary G. Goll
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/273ccd9f47f749a8a1d7aa0e38138ee6
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spelling oai:doaj.org-article:273ccd9f47f749a8a1d7aa0e38138ee62021-12-02T15:35:39ZThe maternal to zygotic transition regulates genome-wide heterochromatin establishment in the zebrafish embryo10.1038/s41467-019-09582-32041-1723https://doaj.org/article/273ccd9f47f749a8a1d7aa0e38138ee62019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09582-3https://doaj.org/toc/2041-1723Eukaryotic genomes are segregated into euchromatin and heterochromatin. Here the authors show that heterochromatin establishment during zebrafish embryo development is controlled by zygotic transcription of miR-430 and subsequent degradation of maternal transcripts encoding the chromatin remodeling protein Smarca2.Kathrin LaueSrivarsha RajshekarAbigail J. CourtneyZachary A. LewisMary G. GollNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kathrin Laue
Srivarsha Rajshekar
Abigail J. Courtney
Zachary A. Lewis
Mary G. Goll
The maternal to zygotic transition regulates genome-wide heterochromatin establishment in the zebrafish embryo
description Eukaryotic genomes are segregated into euchromatin and heterochromatin. Here the authors show that heterochromatin establishment during zebrafish embryo development is controlled by zygotic transcription of miR-430 and subsequent degradation of maternal transcripts encoding the chromatin remodeling protein Smarca2.
format article
author Kathrin Laue
Srivarsha Rajshekar
Abigail J. Courtney
Zachary A. Lewis
Mary G. Goll
author_facet Kathrin Laue
Srivarsha Rajshekar
Abigail J. Courtney
Zachary A. Lewis
Mary G. Goll
author_sort Kathrin Laue
title The maternal to zygotic transition regulates genome-wide heterochromatin establishment in the zebrafish embryo
title_short The maternal to zygotic transition regulates genome-wide heterochromatin establishment in the zebrafish embryo
title_full The maternal to zygotic transition regulates genome-wide heterochromatin establishment in the zebrafish embryo
title_fullStr The maternal to zygotic transition regulates genome-wide heterochromatin establishment in the zebrafish embryo
title_full_unstemmed The maternal to zygotic transition regulates genome-wide heterochromatin establishment in the zebrafish embryo
title_sort maternal to zygotic transition regulates genome-wide heterochromatin establishment in the zebrafish embryo
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/273ccd9f47f749a8a1d7aa0e38138ee6
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