The maternal to zygotic transition regulates genome-wide heterochromatin establishment in the zebrafish embryo
Eukaryotic genomes are segregated into euchromatin and heterochromatin. Here the authors show that heterochromatin establishment during zebrafish embryo development is controlled by zygotic transcription of miR-430 and subsequent degradation of maternal transcripts encoding the chromatin remodeling...
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Nature Portfolio
2019
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oai:doaj.org-article:273ccd9f47f749a8a1d7aa0e38138ee62021-12-02T15:35:39ZThe maternal to zygotic transition regulates genome-wide heterochromatin establishment in the zebrafish embryo10.1038/s41467-019-09582-32041-1723https://doaj.org/article/273ccd9f47f749a8a1d7aa0e38138ee62019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09582-3https://doaj.org/toc/2041-1723Eukaryotic genomes are segregated into euchromatin and heterochromatin. Here the authors show that heterochromatin establishment during zebrafish embryo development is controlled by zygotic transcription of miR-430 and subsequent degradation of maternal transcripts encoding the chromatin remodeling protein Smarca2.Kathrin LaueSrivarsha RajshekarAbigail J. CourtneyZachary A. LewisMary G. GollNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019) |
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Science Q Kathrin Laue Srivarsha Rajshekar Abigail J. Courtney Zachary A. Lewis Mary G. Goll The maternal to zygotic transition regulates genome-wide heterochromatin establishment in the zebrafish embryo |
description |
Eukaryotic genomes are segregated into euchromatin and heterochromatin. Here the authors show that heterochromatin establishment during zebrafish embryo development is controlled by zygotic transcription of miR-430 and subsequent degradation of maternal transcripts encoding the chromatin remodeling protein Smarca2. |
format |
article |
author |
Kathrin Laue Srivarsha Rajshekar Abigail J. Courtney Zachary A. Lewis Mary G. Goll |
author_facet |
Kathrin Laue Srivarsha Rajshekar Abigail J. Courtney Zachary A. Lewis Mary G. Goll |
author_sort |
Kathrin Laue |
title |
The maternal to zygotic transition regulates genome-wide heterochromatin establishment in the zebrafish embryo |
title_short |
The maternal to zygotic transition regulates genome-wide heterochromatin establishment in the zebrafish embryo |
title_full |
The maternal to zygotic transition regulates genome-wide heterochromatin establishment in the zebrafish embryo |
title_fullStr |
The maternal to zygotic transition regulates genome-wide heterochromatin establishment in the zebrafish embryo |
title_full_unstemmed |
The maternal to zygotic transition regulates genome-wide heterochromatin establishment in the zebrafish embryo |
title_sort |
maternal to zygotic transition regulates genome-wide heterochromatin establishment in the zebrafish embryo |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/273ccd9f47f749a8a1d7aa0e38138ee6 |
work_keys_str_mv |
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