Impact of conduction disturbances on left ventricular mass regression and geometry change following transcatheter aortic valve replacement

Abstract Our study aimed to compare the difference of LV mass regression and remodeling in regard of conduction disturbances (CD) following transcatheter aortic valve replacement (TAVR). A prospective analysis of 152 consecutive TAVR patients was performed. 53 patients (34.9%) had CD following TAVR,...

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Autores principales:	Tsung-Yu Ko, Hsien-Li Kao, Ying-Ju Liu, Chih-Fan Yeh, Ching-Chang Huang, Ying-Hsien Chen, Chi-Sheng Hung, Chih-Yang Chan, Lung-Chun Lin, Yih-Sharng Chen, Mao-Shin Lin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/2740705fd8a6499d97c10eff0bdf9521
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spelling	oai:doaj.org-article:2740705fd8a6499d97c10eff0bdf95212021-12-02T17:08:36ZImpact of conduction disturbances on left ventricular mass regression and geometry change following transcatheter aortic valve replacement10.1038/s41598-021-96297-52045-2322https://doaj.org/article/2740705fd8a6499d97c10eff0bdf95212021-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-96297-5https://doaj.org/toc/2045-2322Abstract Our study aimed to compare the difference of LV mass regression and remodeling in regard of conduction disturbances (CD) following transcatheter aortic valve replacement (TAVR). A prospective analysis of 152 consecutive TAVR patients was performed. 53 patients (34.9%) had CD following TAVR, including 30 (19.7%) permanent pacemaker implantation and 23 (15.2%) new left bundle branch block. In 123 patients with 1-year follow-up, significant improvement of LV ejection fraction (LVEF) (baseline vs 12-month: 65.1 ± 13.2 vs 68.7 ± 9.1, P = 0.017) and reduced LV end-systolic volume (LVESV) (39.8 ± 25.8 vs 34.3 ± 17.1, P = 0.011) was found in non-CD group (N = 85), but not in CD group (N = 38). Both groups had significant decrease in LV mass index (baseline vs 12-month: 148.6 ± 36.9 vs. 136.4 ± 34.7 in CD group, p = 0.023; 153.0 ± 50.5 vs. 125.6 ± 35.1 in non-CD group, p < 0.0001). In 46 patients with 3-year follow-up, only non-CD patients (N = 28) had statistically significant decrease in LV mass index (Baseline vs 36-month: 180.8 ± 58.8 vs 129.8 ± 39.1, p = 0.0001). Our study showed the improvement of LV systolic function, reduced LVESV and LV mass regression at 1 year could be observed in patients without CD after TAVR. Sustained LV mass regression within 3-year was found only in patients without CD.Tsung-Yu KoHsien-Li KaoYing-Ju LiuChih-Fan YehChing-Chang HuangYing-Hsien ChenChi-Sheng HungChih-Yang ChanLung-Chun LinYih-Sharng ChenMao-Shin LinNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Tsung-Yu Ko Hsien-Li Kao Ying-Ju Liu Chih-Fan Yeh Ching-Chang Huang Ying-Hsien Chen Chi-Sheng Hung Chih-Yang Chan Lung-Chun Lin Yih-Sharng Chen Mao-Shin Lin Impact of conduction disturbances on left ventricular mass regression and geometry change following transcatheter aortic valve replacement
description	Abstract Our study aimed to compare the difference of LV mass regression and remodeling in regard of conduction disturbances (CD) following transcatheter aortic valve replacement (TAVR). A prospective analysis of 152 consecutive TAVR patients was performed. 53 patients (34.9%) had CD following TAVR, including 30 (19.7%) permanent pacemaker implantation and 23 (15.2%) new left bundle branch block. In 123 patients with 1-year follow-up, significant improvement of LV ejection fraction (LVEF) (baseline vs 12-month: 65.1 ± 13.2 vs 68.7 ± 9.1, P = 0.017) and reduced LV end-systolic volume (LVESV) (39.8 ± 25.8 vs 34.3 ± 17.1, P = 0.011) was found in non-CD group (N = 85), but not in CD group (N = 38). Both groups had significant decrease in LV mass index (baseline vs 12-month: 148.6 ± 36.9 vs. 136.4 ± 34.7 in CD group, p = 0.023; 153.0 ± 50.5 vs. 125.6 ± 35.1 in non-CD group, p < 0.0001). In 46 patients with 3-year follow-up, only non-CD patients (N = 28) had statistically significant decrease in LV mass index (Baseline vs 36-month: 180.8 ± 58.8 vs 129.8 ± 39.1, p = 0.0001). Our study showed the improvement of LV systolic function, reduced LVESV and LV mass regression at 1 year could be observed in patients without CD after TAVR. Sustained LV mass regression within 3-year was found only in patients without CD.
format	article
author	Tsung-Yu Ko Hsien-Li Kao Ying-Ju Liu Chih-Fan Yeh Ching-Chang Huang Ying-Hsien Chen Chi-Sheng Hung Chih-Yang Chan Lung-Chun Lin Yih-Sharng Chen Mao-Shin Lin
author_facet	Tsung-Yu Ko Hsien-Li Kao Ying-Ju Liu Chih-Fan Yeh Ching-Chang Huang Ying-Hsien Chen Chi-Sheng Hung Chih-Yang Chan Lung-Chun Lin Yih-Sharng Chen Mao-Shin Lin
author_sort	Tsung-Yu Ko
title	Impact of conduction disturbances on left ventricular mass regression and geometry change following transcatheter aortic valve replacement
title_short	Impact of conduction disturbances on left ventricular mass regression and geometry change following transcatheter aortic valve replacement
title_full	Impact of conduction disturbances on left ventricular mass regression and geometry change following transcatheter aortic valve replacement
title_fullStr	Impact of conduction disturbances on left ventricular mass regression and geometry change following transcatheter aortic valve replacement
title_full_unstemmed	Impact of conduction disturbances on left ventricular mass regression and geometry change following transcatheter aortic valve replacement
title_sort	impact of conduction disturbances on left ventricular mass regression and geometry change following transcatheter aortic valve replacement
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/2740705fd8a6499d97c10eff0bdf9521
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Impact of conduction disturbances on left ventricular mass regression and geometry change following transcatheter aortic valve replacement

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