Receptor tyrosine kinase ROR1 ameliorates Aβ1–42 induced cytoskeletal instability and is regulated by the miR146a-NEAT1 nexus in Alzheimer’s disease
Abstract Alzheimer’s disease (AD) involves severe cytoskeletal degradation and microtubule disruption. Here, we studied the altered dynamics of ROR1, a Receptor Tyrosine Kinase (RTK), and how it could counter these abnormalities. We found that in an Aβ1–42 treated cell model of AD, ROR1 was signific...
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Autores principales: | Kaushik Chanda, Nihar Ranjan Jana, Debashis Mukhopadhyay |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Acceso en línea: | https://doaj.org/article/27441665e72147fd9531494c4e41b8af |
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