Subcellular domain-dependent molecular hierarchy of SFK and FAK in mechanotransduction and cytokine signaling

Subcellular domain-dependent molecular hierarchy of SFK and FAK in mechanotransduction and cytokine signaling

Abstract Focal adhesion kinase (FAK) and Src family kinases (SFK) are known to play critical roles in mechanotransduction and other crucial cell functions. Recent reports indicate that they reside in different microdomains of the plasma membrane. However, little is known about their subcellular doma...

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Autores principales: Qiaoqiao Wan, ThucNhi TruongVo, Hannah E. Steele, Altug Ozcelikkale, Bumsoo Han, Yingxiao Wang, Junghwan Oh, Hiroki Yokota, Sungsoo Na
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/274b50d63ae34fbeaf40c7a65fcaa9d5
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