Subcellular domain-dependent molecular hierarchy of SFK and FAK in mechanotransduction and cytokine signaling

Abstract Focal adhesion kinase (FAK) and Src family kinases (SFK) are known to play critical roles in mechanotransduction and other crucial cell functions. Recent reports indicate that they reside in different microdomains of the plasma membrane. However, little is known about their subcellular doma...

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Auteurs principaux: Qiaoqiao Wan, ThucNhi TruongVo, Hannah E. Steele, Altug Ozcelikkale, Bumsoo Han, Yingxiao Wang, Junghwan Oh, Hiroki Yokota, Sungsoo Na
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/274b50d63ae34fbeaf40c7a65fcaa9d5
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