Does Bisphosphonate Increase the Sclerosis of Tibial Subchondral Bone in the Progression of Knee Osteoarthritis—A Propensity Score Matching Cohort Study Based on Osteoarthritis Initiative

Bisphosphonate has great potential in KOA therapy, but whether the anti-resorption mechanism of bisphosphonate aggravates sclerosis of subchondral bone remains unclear. We found that bisphosphonate use did not increase sclerosis of subchondral bone in established KOA, perhaps resolving some concerns...

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Bibliographic Details
Main Authors: Mingyang Li, Yong Nie, Yi Zeng, Yuangang Wu, Yuan Liu, Limin Wu, Jiawen Xu, Bin Shen
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
BVF
Online Access:https://doaj.org/article/274ec40d9b854b16816de8dd9c816136
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