The interaction of Ag2O nanoparticles with Escherichia coli: inhibition–sterilization process
Abstract Silver-based antibacterial agents have obtained wide attention due to the fact that bacteria in the environment is ubiquitous, which has become one of the most difficult problems for human health. However, the antibacterial mechanism and process are still inconclusive. Here, Ag2O nanopartic...
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Nature Portfolio
2021
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oai:doaj.org-article:2755392b696e4b1b9596e9b3c6f607f12021-12-02T10:49:34ZThe interaction of Ag2O nanoparticles with Escherichia coli: inhibition–sterilization process10.1038/s41598-021-81305-52045-2322https://doaj.org/article/2755392b696e4b1b9596e9b3c6f607f12021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-81305-5https://doaj.org/toc/2045-2322Abstract Silver-based antibacterial agents have obtained wide attention due to the fact that bacteria in the environment is ubiquitous, which has become one of the most difficult problems for human health. However, the antibacterial mechanism and process are still inconclusive. Here, Ag2O nanoparticles (NPs) with uniform spherical morphology and small size (around 30 nm) were prepared. The as-prepared Ag2O NPs induced high antibacterial activity (100% inhibition ratio) against E. coli. A two-step antibacterial process was proposed and confirmed, which divided into inhibition and sterilization steps. The optical density measurement, malondialdehyde concentration detection, morphologic imaging with electronic microscopy and Fourier transform infrared spectroscopic analysis unveiled the interaction of Ag2O NPs with E. coli, which verified the inhibition–sterilization process we proposed.Danqing LiShuai ChenKe ZhangNan GaoMiao ZhangGadah AlbasherJiangfan ShiChuanyi WangNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021) |
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Medicine R Science Q Danqing Li Shuai Chen Ke Zhang Nan Gao Miao Zhang Gadah Albasher Jiangfan Shi Chuanyi Wang The interaction of Ag2O nanoparticles with Escherichia coli: inhibition–sterilization process |
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Abstract Silver-based antibacterial agents have obtained wide attention due to the fact that bacteria in the environment is ubiquitous, which has become one of the most difficult problems for human health. However, the antibacterial mechanism and process are still inconclusive. Here, Ag2O nanoparticles (NPs) with uniform spherical morphology and small size (around 30 nm) were prepared. The as-prepared Ag2O NPs induced high antibacterial activity (100% inhibition ratio) against E. coli. A two-step antibacterial process was proposed and confirmed, which divided into inhibition and sterilization steps. The optical density measurement, malondialdehyde concentration detection, morphologic imaging with electronic microscopy and Fourier transform infrared spectroscopic analysis unveiled the interaction of Ag2O NPs with E. coli, which verified the inhibition–sterilization process we proposed. |
format |
article |
author |
Danqing Li Shuai Chen Ke Zhang Nan Gao Miao Zhang Gadah Albasher Jiangfan Shi Chuanyi Wang |
author_facet |
Danqing Li Shuai Chen Ke Zhang Nan Gao Miao Zhang Gadah Albasher Jiangfan Shi Chuanyi Wang |
author_sort |
Danqing Li |
title |
The interaction of Ag2O nanoparticles with Escherichia coli: inhibition–sterilization process |
title_short |
The interaction of Ag2O nanoparticles with Escherichia coli: inhibition–sterilization process |
title_full |
The interaction of Ag2O nanoparticles with Escherichia coli: inhibition–sterilization process |
title_fullStr |
The interaction of Ag2O nanoparticles with Escherichia coli: inhibition–sterilization process |
title_full_unstemmed |
The interaction of Ag2O nanoparticles with Escherichia coli: inhibition–sterilization process |
title_sort |
interaction of ag2o nanoparticles with escherichia coli: inhibition–sterilization process |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/2755392b696e4b1b9596e9b3c6f607f1 |
work_keys_str_mv |
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