Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis

Here the authors provide a single-cell characterization of cerebrospinal fluid and blood of newly diagnosed multiple sclerosis (MS) patients, revealing altered composition of lymphocyte and monocyte subsets, validated by other methods including the interrogation of the TFH subset in mouse models of...

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Autores principales:	David Schafflick, Chenling A. Xu, Maike Hartlehnert, Michael Cole, Andreas Schulte-Mecklenbeck, Tobias Lautwein, Jolien Wolbert, Michael Heming, Sven G. Meuth, Tanja Kuhlmann, Catharina C. Gross, Heinz Wiendl, Nir Yosef, Gerd Meyer zu Horste
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2757449eb302442da1fbdc95f72a25a4
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spelling	oai:doaj.org-article:2757449eb302442da1fbdc95f72a25a42021-12-02T14:42:13ZIntegrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis10.1038/s41467-019-14118-w2041-1723https://doaj.org/article/2757449eb302442da1fbdc95f72a25a42020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-14118-whttps://doaj.org/toc/2041-1723Here the authors provide a single-cell characterization of cerebrospinal fluid and blood of newly diagnosed multiple sclerosis (MS) patients, revealing altered composition of lymphocyte and monocyte subsets, validated by other methods including the interrogation of the TFH subset in mouse models of MS.David SchafflickChenling A. XuMaike HartlehnertMichael ColeAndreas Schulte-MecklenbeckTobias LautweinJolien WolbertMichael HemingSven G. MeuthTanja KuhlmannCatharina C. GrossHeinz WiendlNir YosefGerd Meyer zu HorsteNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q David Schafflick Chenling A. Xu Maike Hartlehnert Michael Cole Andreas Schulte-Mecklenbeck Tobias Lautwein Jolien Wolbert Michael Heming Sven G. Meuth Tanja Kuhlmann Catharina C. Gross Heinz Wiendl Nir Yosef Gerd Meyer zu Horste Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis
description	Here the authors provide a single-cell characterization of cerebrospinal fluid and blood of newly diagnosed multiple sclerosis (MS) patients, revealing altered composition of lymphocyte and monocyte subsets, validated by other methods including the interrogation of the TFH subset in mouse models of MS.
format	article
author	David Schafflick Chenling A. Xu Maike Hartlehnert Michael Cole Andreas Schulte-Mecklenbeck Tobias Lautwein Jolien Wolbert Michael Heming Sven G. Meuth Tanja Kuhlmann Catharina C. Gross Heinz Wiendl Nir Yosef Gerd Meyer zu Horste
author_facet	David Schafflick Chenling A. Xu Maike Hartlehnert Michael Cole Andreas Schulte-Mecklenbeck Tobias Lautwein Jolien Wolbert Michael Heming Sven G. Meuth Tanja Kuhlmann Catharina C. Gross Heinz Wiendl Nir Yosef Gerd Meyer zu Horste
author_sort	David Schafflick
title	Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis
title_short	Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis
title_full	Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis
title_fullStr	Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis
title_full_unstemmed	Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis
title_sort	integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/2757449eb302442da1fbdc95f72a25a4
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Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis

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