Emergence of a Plasmid-Encoded Resistance-Nodulation-Division Efflux Pump Conferring Resistance to Multiple Drugs, Including Tigecycline, in <named-content content-type="genus-species">Klebsiella pneumoniae</named-content>

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Emergence of a Plasmid-Encoded Resistance-Nodulation-Division Efflux Pump Conferring Resistance to Multiple Drugs, Including Tigecycline, in <named-content content-type="genus-species">Klebsiella pneumoniae</named-content>

ABSTRACT Transporters belonging to the chromosomally encoded resistance-nodulation-division (RND) superfamily mediate multidrug resistance in Gram-negative bacteria. However, the cotransfer of large gene clusters encoding RND-type pumps from the chromosome to a plasmid appears infrequent, and no pla...

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Auteurs principaux:	Luchao Lv, Miao Wan, Chengzhen Wang, Xun Gao, Qiwen Yang, Sally R. Partridge, Yang Wang, Zhiyong Zong, Yohei Doi, Jianzhong Shen, Peiyao Jia, Qianhua Song, Qianhui Zhang, Jun Yang, Xianhui Huang, Minggui Wang, Jian-Hua Liu
Format:	article
Langue:	EN
Publié:	American Society for Microbiology 2020
Sujets:	Enterobacteriaceae antimicrobial agents efflux pumps mechanisms of resistance multidrug resistance plasmid-mediated resistance Microbiology QR1-502
Accès en ligne:	https://doaj.org/article/275a9babc0f443eb9dcb6b4e5a071b96
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