Mass spectrometry and Monte Carlo method mapping of nanoparticle ligand shell morphology

Determining the arrangement of ligands on a nanoparticle is challenging, given the limitations of existing characterization tools. Here, the authors describe an accessible method for resolving ligand shell morphology that uses simple MALDI-TOF mass spectrometry measurements in conjunction with an op...

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Autores principales: Zhi Luo, Yanfei Zhao, Tamim Darwish, Yue Wang, Jing Hou, Francesco Stellacci
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/275d58fb7dae44779998acf75de1c339
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spelling oai:doaj.org-article:275d58fb7dae44779998acf75de1c3392021-12-02T16:56:59ZMass spectrometry and Monte Carlo method mapping of nanoparticle ligand shell morphology10.1038/s41467-018-06939-y2041-1723https://doaj.org/article/275d58fb7dae44779998acf75de1c3392018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06939-yhttps://doaj.org/toc/2041-1723Determining the arrangement of ligands on a nanoparticle is challenging, given the limitations of existing characterization tools. Here, the authors describe an accessible method for resolving ligand shell morphology that uses simple MALDI-TOF mass spectrometry measurements in conjunction with an open-access Monte Carlo fitting program.Zhi LuoYanfei ZhaoTamim DarwishYue WangJing HouFrancesco StellacciNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Zhi Luo
Yanfei Zhao
Tamim Darwish
Yue Wang
Jing Hou
Francesco Stellacci
Mass spectrometry and Monte Carlo method mapping of nanoparticle ligand shell morphology
description Determining the arrangement of ligands on a nanoparticle is challenging, given the limitations of existing characterization tools. Here, the authors describe an accessible method for resolving ligand shell morphology that uses simple MALDI-TOF mass spectrometry measurements in conjunction with an open-access Monte Carlo fitting program.
format article
author Zhi Luo
Yanfei Zhao
Tamim Darwish
Yue Wang
Jing Hou
Francesco Stellacci
author_facet Zhi Luo
Yanfei Zhao
Tamim Darwish
Yue Wang
Jing Hou
Francesco Stellacci
author_sort Zhi Luo
title Mass spectrometry and Monte Carlo method mapping of nanoparticle ligand shell morphology
title_short Mass spectrometry and Monte Carlo method mapping of nanoparticle ligand shell morphology
title_full Mass spectrometry and Monte Carlo method mapping of nanoparticle ligand shell morphology
title_fullStr Mass spectrometry and Monte Carlo method mapping of nanoparticle ligand shell morphology
title_full_unstemmed Mass spectrometry and Monte Carlo method mapping of nanoparticle ligand shell morphology
title_sort mass spectrometry and monte carlo method mapping of nanoparticle ligand shell morphology
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/275d58fb7dae44779998acf75de1c339
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AT tamimdarwish massspectrometryandmontecarlomethodmappingofnanoparticleligandshellmorphology
AT yuewang massspectrometryandmontecarlomethodmappingofnanoparticleligandshellmorphology
AT jinghou massspectrometryandmontecarlomethodmappingofnanoparticleligandshellmorphology
AT francescostellacci massspectrometryandmontecarlomethodmappingofnanoparticleligandshellmorphology
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