Information diversity in individual auditory cortical neurons is associated with functionally distinct coordinated neuronal ensembles

Abstract Neuronal activity in auditory cortex is often highly synchronous between neighboring neurons. Such coordinated activity is thought to be crucial for information processing. We determined the functional properties of coordinated neuronal ensembles (cNEs) within primary auditory cortical (AI)...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Jermyn Z. See, Natsumi Y. Homma, Craig A. Atencio, Vikaas S. Sohal, Christoph E. Schreiner
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/2762375115b24b1398ed54f66ac09eba
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:2762375115b24b1398ed54f66ac09eba
record_format	dspace
spelling	oai:doaj.org-article:2762375115b24b1398ed54f66ac09eba2021-12-02T14:03:44ZInformation diversity in individual auditory cortical neurons is associated with functionally distinct coordinated neuronal ensembles10.1038/s41598-021-83565-72045-2322https://doaj.org/article/2762375115b24b1398ed54f66ac09eba2021-02-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-83565-7https://doaj.org/toc/2045-2322Abstract Neuronal activity in auditory cortex is often highly synchronous between neighboring neurons. Such coordinated activity is thought to be crucial for information processing. We determined the functional properties of coordinated neuronal ensembles (cNEs) within primary auditory cortical (AI) columns relative to the contributing neurons. Nearly half of AI cNEs showed robust spectro-temporal receptive fields whereas the remaining cNEs showed little or no acoustic feature selectivity. cNEs can therefore capture either specific, time-locked information of spectro-temporal stimulus features or reflect stimulus-unspecific, less-time specific processing aspects. By contrast, we show that individual neurons can represent both of those aspects through membership in multiple cNEs with either high or absent feature selectivity. These associations produce functionally heterogeneous spikes identifiable by instantaneous association with different cNEs. This demonstrates that single neuron spike trains can sequentially convey multiple aspects that contribute to cortical processing, including stimulus-specific and unspecific information.Jermyn Z. SeeNatsumi Y. HommaCraig A. AtencioVikaas S. SohalChristoph E. SchreinerNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Jermyn Z. See Natsumi Y. Homma Craig A. Atencio Vikaas S. Sohal Christoph E. Schreiner Information diversity in individual auditory cortical neurons is associated with functionally distinct coordinated neuronal ensembles
description	Abstract Neuronal activity in auditory cortex is often highly synchronous between neighboring neurons. Such coordinated activity is thought to be crucial for information processing. We determined the functional properties of coordinated neuronal ensembles (cNEs) within primary auditory cortical (AI) columns relative to the contributing neurons. Nearly half of AI cNEs showed robust spectro-temporal receptive fields whereas the remaining cNEs showed little or no acoustic feature selectivity. cNEs can therefore capture either specific, time-locked information of spectro-temporal stimulus features or reflect stimulus-unspecific, less-time specific processing aspects. By contrast, we show that individual neurons can represent both of those aspects through membership in multiple cNEs with either high or absent feature selectivity. These associations produce functionally heterogeneous spikes identifiable by instantaneous association with different cNEs. This demonstrates that single neuron spike trains can sequentially convey multiple aspects that contribute to cortical processing, including stimulus-specific and unspecific information.
format	article
author	Jermyn Z. See Natsumi Y. Homma Craig A. Atencio Vikaas S. Sohal Christoph E. Schreiner
author_facet	Jermyn Z. See Natsumi Y. Homma Craig A. Atencio Vikaas S. Sohal Christoph E. Schreiner
author_sort	Jermyn Z. See
title	Information diversity in individual auditory cortical neurons is associated with functionally distinct coordinated neuronal ensembles
title_short	Information diversity in individual auditory cortical neurons is associated with functionally distinct coordinated neuronal ensembles
title_full	Information diversity in individual auditory cortical neurons is associated with functionally distinct coordinated neuronal ensembles
title_fullStr	Information diversity in individual auditory cortical neurons is associated with functionally distinct coordinated neuronal ensembles
title_full_unstemmed	Information diversity in individual auditory cortical neurons is associated with functionally distinct coordinated neuronal ensembles
title_sort	information diversity in individual auditory cortical neurons is associated with functionally distinct coordinated neuronal ensembles
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/2762375115b24b1398ed54f66ac09eba
work_keys_str_mv	AT jermynzsee informationdiversityinindividualauditorycorticalneuronsisassociatedwithfunctionallydistinctcoordinatedneuronalensembles AT natsumiyhomma informationdiversityinindividualauditorycorticalneuronsisassociatedwithfunctionallydistinctcoordinatedneuronalensembles AT craigaatencio informationdiversityinindividualauditorycorticalneuronsisassociatedwithfunctionallydistinctcoordinatedneuronalensembles AT vikaasssohal informationdiversityinindividualauditorycorticalneuronsisassociatedwithfunctionallydistinctcoordinatedneuronalensembles AT christopheschreiner informationdiversityinindividualauditorycorticalneuronsisassociatedwithfunctionallydistinctcoordinatedneuronalensembles
_version_	1718392068874698752

Information diversity in individual auditory cortical neurons is associated with functionally distinct coordinated neuronal ensembles

Ejemplares similares